Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures

• Published in: Neuroscience bulletin Vol. 30; no. 6; pp. 913 - 922
• Main Authors: Dai, Yun-Jian, Xu, Zheng-Hao, Feng, Bo, Xu, Ceng-Lin, Zhao, Hua-Wei, Wu, Deng-Chang, Hu, Wei-Wei, Chen, Zhong
• Format: Journal Article
• Language: English
• Published: Singapore Springer Singapore 01.12.2014
• Subjects: Anatomy; Anesthesiology; Animals; Biomedical and Life Sciences; Biomedicine; Convulsants; Disease Models, Animal; Disease Susceptibility; Electroshock; Female; Fever; Human Physiology; Male; Neurology; Neurosciences; Original; Original Article; Pain Medicine; Pentylenetetrazole; Rats; Seizures - etiology; Sex Characteristics; 性别差异; 惊厥; 成年大鼠; 收购; 敏感性; 早期; 癫痫; 高热; epilepsy; complex febrile seizures; gender difference; seizure susceptibility; IL-1β

Gender differences are involved in many neurological disorders including epilepsy. However, little is known about the effect of gender difference on the risk of epilepsy in adults with a specific early pathological state such as complex febrile seizures（FSs） in infancy. Here we used a well-establish...