Malaria and leishmaniasis: Updates on co-infection
Malaria and leishmaniasis are endemic parasitic diseases in tropical and subtropical countries. Although the overlap of these diseases in the same host is frequently described, co-infection remains a neglected issue in the medical and scientific community. The complex relationship of concomitant inf...
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Published in | Frontiers in immunology Vol. 14; p. 1122411 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Switzerland
Frontiers Media S.A
21.02.2023
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Subjects | |
Online Access | Get full text |
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Summary: | Malaria and leishmaniasis are endemic parasitic diseases in tropical and subtropical countries. Although the overlap of these diseases in the same host is frequently described, co-infection remains a neglected issue in the medical and scientific community. The complex relationship of concomitant infections with
spp. and
spp. is highlighted in studies of natural and experimental co-infections, showing how this "dual" infection can exacerbate or suppress an effective immune response to these protozoa. Thus, a
infection preceding or following
infection can impact the clinical course, accurate diagnosis, and management of leishmaniasis, and vice versa. The concept that in nature we are affected by concomitant infections reinforces the need to address the theme and ensure its due importance. In this review we explore and describe the studies available in the literature on
spp. and
spp. co-infection, the scenarios, and the factors that may influence the course of these diseases. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 Reviewed by: Fariborz Bahrami, Pasteur Institute of Iran, Iran; Sonali Das, National Heart, Lung, and Blood Institute (NIH), United States Edited by: Dario S. Zamboni, University of São Paulo, Brazil This article was submitted to Parasite Immunology, a section of the journal Frontiers in Immunology |
ISSN: | 1664-3224 1664-3224 |
DOI: | 10.3389/fimmu.2023.1122411 |