In Vitro Selection and Characterization of Human Immunodeficiency Virus Type 1 Variants with Increased Resistance to ABT-378, a Novel Protease Inhibitor

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Published inJournal of Virology Vol. 72; no. 9; pp. 7532 - 7541
Main Authors Carrillo, A, Stewart, K D, Sham, H L, Norbeck, D W, Kohlbrenner, W E, Leonard, J M, Kempf, D J, Molla, A
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 01.09.1998
Subjects
AIDS/HIV
Amino Acid Sequence
Animal Viruses
Animals
Anti-HIV Agents - chemistry
Anti-HIV Agents - pharmacology
Binding Sites
Cell Line, Transformed
COS Cells
Drug Resistance, Microbial
Genetic Variation
HIV Protease - drug effects
HIV Protease - genetics
HIV Protease - metabolism
HIV-1 - drug effects
HIV-1 - enzymology
HIV-1 - genetics
Humans
Lopinavir
Molecular Sequence Data
Molecular Structure
Mutation
Pyrimidinones - chemistry
Pyrimidinones - pharmacology
Ritonavir - pharmacology
Saquinavir - pharmacology
Tumor Cells, Cultured
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Summary:Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue JVI About JVI Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy JVI RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0022-538X Online ISSN: 1098-5514 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to JVI .asm.org, visit: JVI       
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Corresponding author. Mailing address: D-7BP, Strategic Technical Product Development, Building AP8B, Abbott Laboratories, 100 Abbott Park Rd., Abbott Park, IL 60064. Phone: (847) 937-3179. Fax: (847) 938-3721. E-mail: alex.carrillo@add.ssw.abbott.com.
ISSN:0022-538X
1098-5514
DOI:10.1128/jvi.72.9.7532-7541.1998