Effect of Smoking on Common Carotid Artery Wall Elasticity Evaluated by Echo Tracking Technique

• Published in: Ultrasound in medicine & biology Vol. 40; no. 3; pp. 643 - 649
• Main Authors: Zhang, Pu, Guo, Ruijun, Li, Zhian, Xiao, Dan, Ma, Lin, Huang, Pintong, Wang, Chen
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 01.03.2014
• Subjects: Adult; Algorithms; Arterial wall elasticity; Carotid Artery Diseases - diagnostic imaging; Carotid Artery Diseases - physiopathology; Carotid Artery, Common - diagnostic imaging; Carotid Artery, Common - physiopathology; Carotid Intima-Media Thickness; China - epidemiology; Common carotid artery; Echo tracking; Elasticity Imaging Techniques - methods; Elasticity Imaging Techniques - statistics & numerical data; Female; Humans; Image Enhancement - methods; Image Interpretation, Computer-Assisted - methods; Male; Middle Aged; Prevalence; Radiology; Reproducibility of Results; Risk Assessment; Sensitivity and Specificity; Smoking; Smoking - epidemiology; Smoking - physiopathology; Ultrasonography; Arterial wall elasticity; Common carotid artery; Echo tracking; Ultrasonography; Smoking
• ISSN: 0301-5629; 1879-291X
• DOI: 10.1016/j.ultrasmedbio.2013.10.009

Abstract The aim of this study was to examine the applicability of echo tracking to evaluation of common carotid artery wall elasticity in smokers and the effects of hypertension, hyperlipidemia and hyperglycemia on common carotid artery wall elasticity in smokers. Subjects were divided into three groups based on smoking status and presence of complications: group A (healthy control group), group B1 (simple smoking group) and group B2 (smoking with complications group). Complications included one or several symptoms of hypertension, hyperlipidemia and hyperglycemia. Intima-media thickness (IMT) of the common carotid artery was measured with ultrasound, and wall stiffness index(β), pressure-strain elasticity modulus ( Ep ), arterial compliance, augmentation index and local pulse wave velocity (PWVβ) were measured with echo tracking. We also determined the systolic ( Ds ) and diastolic ( Dd ) lumen diameters of the common carotid artery and systolic ( Ps ) and diastolic ( Pd ) pressures. The differences in β, Ep and PWVβ among the three groups in this study were statistically significant ( p  < 0.05). Augmentation index was increased in group B2 compared with groups B1 and A, with the differences being statistically significant ( p  < 0.05). Differences in augmentation index between groups B1 and A, differences in arterial compliance among the three groups and differences in intima-media thickness among the three groups were not statistically significant ( p  > 0.05), but differences in Ds and Dd among the three groups were statistically significant ( p  < 0.05). Differences in Ps and Pd between groups A and B1 were not statistically significant ( p  > 0.05), whereas those between groups B1 and B2 were statistically significant ( p  < 0.05). Echo tracking can be used to quantitatively evaluate the effect of smoking on common carotid artery wall elasticity and the effects of hypertension, hyperlipidemia and hyperglycemia on common carotid artery wall elasticity in smokers.