Sugar and dental caries: a review of human studies [Sucrose]

• Published in: Science (American Association for the Advancement of Science) Vol. 217; no. 4558; pp. 418 - 423
• Main Author: Newbrun, Ernest
• Format: Journal Article
• Language: English
• Published: United States The American Association for the Advancement of Science 30.07.1982; American Association for the Advancement of Science
• Subjects: Adolescent; Cariogenic Agents; Cereal foods; Child; Child health; Child, Preschool; Children; Dental caries; Dental Caries - epidemiology; Dental Caries - etiology; Diet; Diet, Cariogenic; Feeding Behavior; Food; Food Preferences; Gingiva; Health aspects; Humans; Longitudinal Studies; Physiological aspects; Soft drinks; Statistical significance; Sucrose - adverse effects; Sucrose - metabolism; Sugar; Sugar in the body; Sugars; Sweetening Agents - pharmacology; Teeth
• ISSN: 0036-8075; 1095-9203
• DOI: 10.1126/science.7046052

Studies of special population groups, epidemiological surveys, controlled longitudinal studies of humans, and longitudinal studies on the effect of sugar substitutes indicate that frequent or high intake of sugary foods predisposes to dental decay. The relation is not always clear-cut, and most studies have important methodological problems and limitations. Longitudinal measurements of caries increments combined with multiple dietary histories are needed to clarify the association between caries and eating habits. The relative cariogenicity of specific foods can be assessed by a combination of in vitro tests, human in vivo tests, and experimental caries in animals. Human diets, however, vary in food items eaten and the frequency and sequence of eating, and these factors can affect the cariogenicity of a food. Therefore, reported correlations must be interpreted with caution.