Clinical experience with portable cardiopulmonary bypass in cardiac arrest patients

• Published in: The Annals of thoracic surgery Vol. 50; no. 3; pp. 437 - 441
• Main Authors: Hartz, Renée, LoCicero, Joseph, Sanders, John H., Frederiksen, James W., Joob, Axel W., Michaelis, Lawrence L.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.09.1990; Elsevier Science
• Subjects: Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Cardiopulmonary Bypass - adverse effects; Cardiopulmonary Bypass - methods; Emergencies; Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care; Female; Heart Arrest - mortality; Heart Arrest - physiopathology; Heart Arrest - therapy; Hemodynamics; Humans; Intensive care medicine; Medical sciences; Monitoring, Physiologic; Resuscitation - methods; Survival Rate; Cardiopulmonary bypass; Human; Portable; Intensive cardiocirculatory care; Cardiocirculatory arrest; Prognosis; Device; Cardiovascular disease; Extracorporeal circuit
• ISSN: 0003-4975; 1552-6259
• DOI: 10.1016/0003-4975(90)90490-W

To evaluate the use of portable cardiopulmonary bypass as a resuscitative tool and its impact on long-term survival of patients in cardiac arrest, we reviewed the results of 32 consecutive patients resuscitated by cardiopulmonary bypass for cardiac arrest or severe hemodynamic compromise at Northwestern Memorial Hospital over a 2-year period. Overall survival was 12.5%. Only 1 (3.4%) of the 29 patients who had cardiac arrest survived and left the hospital. All 3 patients who had severe hemodynamic compromise but not cardiac arrest were long-term survivors. Our study suggests that portable cardiopulmonary support systems used as a resuscitative tool do not prolong the survival of most cardiac arrest patients but may be useful for patients with shock due to mechanical causes and for those with profound hemodynamic compromise due to ischemia or myocardial infarction. Portable heart-lung machines can provide patients with excellent hemodynamic support; however, neurological or cardiac recovery is unlikely once cardiac arrest occurs.