Anaphylaxis to cisatracurium following negative skin testing

• Published in: Anaesthesia and intensive care Vol. 33; no. 6; pp. 816 - 819
• Main Authors: FRASER, B. A, SMARTS, J. A
• Format: Journal Article
• Language: English
• Published: Edgecliff Anaesthesia and Intensive Care 01.12.2005; Sage Publications Ltd
• Subjects: Anaphylaxis - chemically induced; Anaphylaxis - drug therapy; Anaphylaxis - physiopathology; Anesthesia; Anesthesia, General - adverse effects; Anesthesia, General - methods; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Atracurium - administration & dosage; Atracurium - adverse effects; Atracurium - analogs & derivatives; Biological and medical sciences; Brain Neoplasms - diagnosis; Brain Neoplasms - surgery; False Negative Reactions; Follow-Up Studies; Humans; Male; Medical sciences; Meningioma - diagnosis; Meningioma - surgery; Middle Aged; Neuromuscular Blocking Agents - administration & dosage; Neuromuscular Blocking Agents - adverse effects; Neurosurgical Procedures - methods; Patch Tests; Risk Assessment; Immunopathology; Allergy; Anaphylaxis; Anesthesia; ANAPHYLAXIS: cisatracurium; negative skin test; Skin test
• ISSN: 0310-057X; 1448-0271
• DOI: 10.1177/0310057x0503300620

General anaesthesia for the patient with a history of anaesthesia-related anaphylaxis is challenging. Precautions against anaphylaxis and the use of skin test negative drugs can reduce but not eliminate the risk. In the majority of such cases, subsequent anaesthesia is uneventful. However, the absence of a clearly identified triggering agent increases the difficulties facing the anaesthetist. We present a case of anaphylaxis to cisatracurium following a negative skin test.