Correlation between positive serology for Plasmodium vivax-like/ Plasmodium simiovale malaria parasites in the human and anopheline populations in the State of Acre, Brazil

• Published in: Transactions of the Royal Society of Tropical Medicine and Hygiene Vol. 92; no. 2; pp. 149 - 151
• Main Authors: Marrelli, Mauro Toledo, Branquinho, Maria Stela, Esther Hoffmann, Erika Hellena, Taipe-Lagos, Carmen Beatriz, Natal, Delsio, Kloetzel, Judith Kardos
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.03.1998; Royal Society of Tropical Medicine and Hygiene; Elsevier
• Subjects: Adult; Animals; Anopheles - parasitology; Anopheles deaneorum; Anopheles oswaldoi; Antibodies, Protozoan - analysis; Biological and medical sciences; Brazil; Brazil - epidemiology; Enzyme-Linked Immunosorbent Assay; Female; Human protozoal diseases; Humans; Infectious diseases; Insect Vectors; Malaria; Malaria, Vivax - epidemiology; Malaria, Vivax - immunology; Male; Medical sciences; Parasitic diseases; Plasmodium simiovale; Plasmodium vivax - immunology; Plasmodium vivax-like species; Protozoal diseases; seroprevalence; Tropical medicine; South America; Brazil; America; Plasmodium vivax-like species; Anopheles oswaldoi; Plasmodium simiovale; seroprevalence; Brazil; malaria; Anopheles deaneorum; like species; Human; Protozoa; Apicomplexa; Protozoal disease; Prevalence; Malaria; Insecta; Parasitosis; Epidemiology; Infection; Plasmodium vivax; Anopheles; Arthropoda; Culicidae; Parasitism rate; Invertebrata; Diptera
• ISSN: 0035-9203; 1878-3503
• DOI: 10.1016/S0035-9203(98)90723-4

Antibodies against the Plasmodium vivax-like/ P. simiovale malaria parasite circumsporozoite repeat peptide (APGANQEGGAA) 3 were determined by enzyme-linked immunosorbent assay (ELISA) in 120 sera randomly collected in 1994 from adults in 3 localities of the malaria endemic area in the State of Acre, Brazil; antibody was detected in 18 (15%). A ‘sandwich’ ELISA using monoclonal antibody (mab) Pam 172, directed against the same peptide, was carried out on 1207 Anopheles oswaldoi, 12 of which (1.0%) were positive, and 168 A. deaneorum, 2 of which (1.2%) were positive. This is the first report of serological detection of the P. vivax-like parasite in anophelines and the first report linking anopheline to human serology for this parasite in the same geographical area. It is an additional indication that A. oswaldoi is a malaria vector in Acre.