In vivo validation of a one-dimensional finite-element method for predicting blood flow in cardiovascular bypass grafts
Current practice in vascular surgery utilizes only diagnostic and empirical data to plan treatments and does not enable quantitative a priori prediction of the outcomes of interventions. We have previously described a new approach to vascular surgery planning based on solving the governing equations...
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Published in | IEEE transactions on biomedical engineering Vol. 50; no. 6; pp. 649 - 656 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
New York, NY
IEEE
01.06.2003
Institute of Electrical and Electronics Engineers The Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Subjects | |
Online Access | Get full text |
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Summary: | Current practice in vascular surgery utilizes only diagnostic and empirical data to plan treatments and does not enable quantitative a priori prediction of the outcomes of interventions. We have previously described a new approach to vascular surgery planning based on solving the governing equations of blood flow in patient-specific models. A one-dimensional finite-element method was used to simulate blood flow in eight porcine thoraco-thoraco aortic bypass models. The predicted flow rate was compared to in vivo data obtained using cine phase-contrast magnetic resonance imaging. The mean absolute difference between computed and measured flow distribution in the stenosed aorta was found to be 4.2% with the maximum difference of 10.6% and a minimum difference of 0.4%. Furthermore, the sensitivity of the flow rate and distribution with respect to stenosis and branch losses were quantified. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1 |
ISSN: | 0018-9294 1558-2531 |
DOI: | 10.1109/TBME.2003.812201 |