Discontinuous transcription

• Published in: Nucleus (Austin, Tex.) Vol. 9; no. 1; pp. 149 - 160
• Main Authors: Smirnov, Evgeny, Hornáček, Matúš, Vacík, Tomáš, Cmarko, Dušan, Raška, Ivan
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.01.2018
• Subjects: bursting; discontinuous gene expression; kinetics; Pulsing transcription; Review; transcriptional fluctuation; discontinuous gene expression; kinetics; bursting; Pulsing transcription; transcriptional fluctuation

Numerous studies based on new single-cell and single-gene techniques show that individual genes can be transcribed in short bursts or pulses accompanied by changes in pulsing frequencies. Since so many examples of such discontinuous or fluctuating transcription have been found from prokaryotes to ma...