Brachial-ankle pulse wave velocity predicts all-cause mortality in the general population: findings from the Takashima study, Japan

Brachial-ankle pulse wave velocity (baPWV) is a relatively new non-invasive measure of arterial stiffness obtained using an automated system. We assessed the relationship between baPWV and 6.5-year overall mortality from the Takashima cohort study. The baPWV was measured in 2642 participants at base...

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Published inHypertension research Vol. 33; no. 9; pp. 922 - 925
Main Authors Turin, Tanvir Chowdhury, Kita, Yoshikuni, Rumana, Nahid, Takashima, Naoyuki, Kadota, Aya, Matsui, Kenji, Sugihara, Hideki, Morita, Yutaka, Nakamura, Yasuyuki, Miura, Katsuyuki, Ueshima, Hirotsugu
Format Journal Article
LanguageEnglish
Published England 01.09.2010
Subjects
Adult
Aged
Ankle Brachial Index
Blood Flow Velocity
Female
Humans
Japan - epidemiology
Longitudinal Studies
Male
Middle Aged
Mortality
Pulsatile Flow - physiology
Japan
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Summary:Brachial-ankle pulse wave velocity (baPWV) is a relatively new non-invasive measure of arterial stiffness obtained using an automated system. We assessed the relationship between baPWV and 6.5-year overall mortality from the Takashima cohort study. The baPWV was measured in 2642 participants at baseline. When participants were divided into tertiles, all-cause mortality increased significantly as baPWV increased (P<0.001). Participants in the highest baPWV tertile showed an increased risk of all-cause mortality evidenced by a multivariable adjusted hazard ratio of 6.8 (95% confidence interval: 1.4-32.8) as compared with the lowest tertile. The present study demonstrated that increased baPWV is an independent predictor of all-cause mortality in the Japanese population.
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ISSN:0916-9636
1348-4214
DOI:10.1038/hr.2010.103