Use of Ventriculoperitoneal Shunts to Treat Uncontrollable Intracranial Hypertension in Patients Who Have Cryptococcal Meningitis without Hydrocephalus

Between 1997 and 2000, 4 human immunodeficiency virus-negative patients in our institution had cryptococcal meningitis with uncontrollable intracranial hypertension. All 4 patients were treated with antifungal drugs as well as ventriculoperitoneal (VP) shunts for intracranial hypertension. Neurologi...

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Published inClinical infectious diseases Vol. 34; no. 12; pp. e64 - e68
Main Authors Liliang, Po-Chou, Liang, Cheng-Loong, Chang, Wen-Neng, Lu, Kang, Lu, Cheng-Hsien
Format Journal Article
LanguageEnglish
Published United States The University of Chicago Press 15.06.2002
Subjects
Adult
Aged
Antifungal Agents - therapeutic use
Female
Humans
Hydrocephalus - etiology
Intracranial Hypertension - etiology
Intracranial Hypertension - therapy
Male
Meningitis, Cryptococcal - complications
Meningitis, Cryptococcal - drug therapy
Middle Aged
Ventriculoperitoneal Shunt
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Summary:Between 1997 and 2000, 4 human immunodeficiency virus-negative patients in our institution had cryptococcal meningitis with uncontrollable intracranial hypertension. All 4 patients were treated with antifungal drugs as well as ventriculoperitoneal (VP) shunts for intracranial hypertension. Neurological deficits that were unresponsive to pharmacologic treatment were resolved by use of the VP shunt. Uncontrollable elevation of intracranial pressure associated with cryptococcal meningitis can be resolved by use of a VP shunt, even when imaging studies do not reveal hydrocephalus.
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ISSN:1058-4838
1537-6591
DOI:10.1086/340525