Studies on Phenazines. XV. The Ring Cleavage of Phenazine. (1). 2, 3-Quinoxalinedicarboxylic Acid

Oxidation of phenazine gave 2, 3-quinoxalinedicarboxylic acid in the yield of 70%, together with small amount of another acidic substance. The latter was obtained by the similar oxidation of 1-and 2-methoxyphenazine in the yields of 45% and 24%, respectively. From quinoxalinedicarboxylic acid, 2-qui...

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Bibliographic Details
Published inPharmaceutical Bulletin Vol. 5; no. 3; pp. 277 - 279
Main Authors Yosioka, Itiro, Otomasu, Hirotaka
Format Journal Article
LanguageEnglish
Published Japan The Pharmaceutical Society of Japan 1957
Subjects
Cytokinesis
Heterocyclic Compounds
Morpholines
Old Medline
Phenazines
HETEROCYCLIC COMPOUNDS
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Summary:Oxidation of phenazine gave 2, 3-quinoxalinedicarboxylic acid in the yield of 70%, together with small amount of another acidic substance. The latter was obtained by the similar oxidation of 1-and 2-methoxyphenazine in the yields of 45% and 24%, respectively. From quinoxalinedicarboxylic acid, 2-quinoxaline-carbonamide, -carbohydrazide, and -hydroxamic acid were prepared and their antitubercular activities tested.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0369-9471
1881-1345
DOI:10.1248/cpb1953.5.277