Apparent 'auto'-anti-DE of the IgA and IgG classes in a 16-year-old girl with a mature cystic ovarian teratoma

Prior to the removal of a mature cystic teratoma in a girl, aged 16, we had difficulties in Rh typing due to immunoglobulin coating of the red blood cells (RBCs). Further examination revealed the presence of anti-D and anti-E antibodies; the clinical course and the serological characteristics indica...

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Bibliographic Details
Published inVox sanguinis Vol. 53; no. 2; p. 102
Main Authors Schönitzer, D, Kilga-Nogler, S
Format Journal Article
LanguageEnglish
Published England 01.01.1987
Subjects
Adolescent
Autoantibodies - immunology
Dermoid Cyst - genetics
Dermoid Cyst - immunology
Female
Humans
Immunoglobulin A - immunology
Immunoglobulin G - immunology
Ovarian Neoplasms - genetics
Ovarian Neoplasms - immunology
Rh-Hr Blood-Group System - genetics
Rh-Hr Blood-Group System - immunology
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Summary:Prior to the removal of a mature cystic teratoma in a girl, aged 16, we had difficulties in Rh typing due to immunoglobulin coating of the red blood cells (RBCs). Further examination revealed the presence of anti-D and anti-E antibodies; the clinical course and the serological characteristics indicated that the Rh antibodies originated from the tumor itself, that is, there was alloantibody formation against the host's RBCs. The specific alloantibody production, as well as the fact that these antibodies belong to the IgA and IgG1 classes provide further evidence for the pluripotency of mature cystic ovarian teratomas.
ISSN:0042-9007
DOI:10.1111/j.1423-0410.1987.tb04927.x