Long-term outcome of transcatheter coil closure of small to large patent ductus arteriosus

• Published in: Catheterization and cardiovascular interventions Vol. 47; no. 4; pp. 457 - 461
• Main Authors: Patel, Hitendra T., Cao, Qi-Ling, Rhodes, Jonathan, Hijazi, Ziyad M.
• Format: Journal Article
• Language: English
• Published: New York John Wiley & Sons, Inc 01.08.1999
• Subjects: Adolescent; Adult; catheter intervention; Child; Child, Preschool; coil; Ductus Arteriosus - pathology; Ductus Arteriosus, Patent - diagnostic imaging; Ductus Arteriosus, Patent - pathology; Ductus Arteriosus, Patent - therapy; Echocardiography; Embolization, Therapeutic - adverse effects; Embolization, Therapeutic - instrumentation; Fluoroscopy; Follow-Up Studies; Humans; Infant; Infant, Newborn; Middle Aged; Radiography, Interventional; transcatheter closure; Treatment Outcome
• ISSN: 1522-1946; 1522-726X
• DOI: 10.1002/(SICI)1522-726X(199908)47:4<457::AID-CCD15>3.0.CO;2-A

Coil closure of patent ductus arteriosus (PDA) has become an accepted alternative to surgical closure in most pediatric cardiac centers. However, little is known about the mid‐ to long‐term outcome of this procedure. Therefore, we evaluated the immediate, short‐, and long‐term outcome of transcatheter coil closure (TCC) of PDA using single or multiple Gianturco coils or the Gianturco‐Grifka Vascular Occlusive Device (GGVOD). One hundred forty‐nine patients underwent an attempt at TCC of their PDAs at a median age of 2.4 years (2 weeks to 55 years) and median weight of 13.5 kg (2.3–87 kg). There were 33 patients < 1 year of age. The median PDA minimal diameter was 2 mm (0.4–7 mm) with 26 patients whose PDA minimal diameter was > 4 mm. A 4 Fr catheter was used for coil deployment in 136 patients, a 3 Fr in 4, and an 8 Fr in 4 patients who received the GGVOD. A single coil was used in 77 patients and multiple coils (2–6) were used in 66 patients. One hundred forty‐six patients had successful closure (142 had immediate complete closure and 4 had residual shunt), 3 patients failed the initial attempt (2 underwent surgical ligation and 1 had a successful second attempt a year later). Of the four patients with residual shunt, three underwent a second procedure with implantation of 1–3 coils resulting in complete closure in all and one patient had spontaneous resolution of the residual shunt. Complications were encountered in nine patients: six had coil migration with successful retrieval in four; two had left pulmonary artery stenosis (2.4 kg and 6.3 kg infants), and one patient had loss of femoral arterial pulse. The median fluoroscopy time was 16 min (2–152 min). One hundred forty‐two patients had the procedure as an outpatient, five patients stayed greater than 24 hr, and two of these patients were in hospital for 1 month for noncardiac reasons. At a median follow‐up interval of 3.0 years (1 month to 5.1 years), there were no episodes of delayed coil migration, delayed recanalization, thromboembolic episodes, or bacterial endocarditis. Lung perfusion scans performed at a median follow‐up interval of 1.6 years in 31 patients who received multiple coils revealed 45% ± 5% blood flow to the left lung. Long‐term follow‐up of coil closure of PDA indicates that the technique is safe and effective for most pa‐tients with PDA up to a diameter of 7 mm. Cathet. Cardiovasc. Intervent. 47:457–461, 1999. © 1999 Wiley‐Liss, Inc.