Dissecting Chromatin Architecture for Novel Cardiovascular Disease Targets
Unraveling the principles of cardiac chromatin organization for next generation therapies in heart disease
Saved in:
| Published in | Circulation (New York, N.Y.) Vol. 140; no. 6; pp. 446 - 448 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
by the American College of Cardiology Foundation and the American Heart Association, Inc
06.08.2019
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0009-7322 1524-4539 1524-4539 |
| DOI | 10.1161/CIRCULATIONAHA.119.039287 |
Cover
| Abstract | Unraveling the principles of cardiac chromatin organization for next generation therapies in heart disease |
|---|---|
| AbstractList | Unraveling the principles of cardiac chromatin organization for next generation therapies in heart disease |
| Author | Foo, Roger Sik-Yin Rosa-Garrido, Manuel Vondriska, Thomas M. Anene-Nzelu, Chukwuemeka George |
| AuthorAffiliation | Cardiovascular Research Institute, National University Health System, Centre for Translational Medicine, Singapore (R.S.-Y.F., C.G.A.-N.). Genome Institute of Singapore (C.G.A.-N.). Departments of Anesthesiology, Medicine and Physiology, David Geffen School of Medicine at UCLA (M.R.-G., T.M.V.) |
| AuthorAffiliation_xml | – name: Cardiovascular Research Institute, National University Health System, Centre for Translational Medicine, Singapore (R.S.-Y.F., C.G.A.-N.). Genome Institute of Singapore (C.G.A.-N.). Departments of Anesthesiology, Medicine and Physiology, David Geffen School of Medicine at UCLA (M.R.-G., T.M.V.) – name: 3 Departments of Anesthesiology, Medicine and Physiology, David Geffen School of Medicine at UCLA, Los Angeles, USA – name: 1 Cardiovascular Research Institute, National University Health System, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore – name: 2 Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore |
| Author_xml | – sequence: 1 givenname: Roger surname: Foo middlename: Sik-Yin fullname: Foo, Roger Sik-Yin organization: Cardiovascular Research Institute, National University Health System, Centre for Translational Medicine, Singapore (R.S.-Y.F., C.G.A.-N.). Genome Institute of Singapore (C.G.A.-N.). Departments of Anesthesiology, Medicine and Physiology, David Geffen School of Medicine at UCLA (M.R.-G., T.M.V.) – sequence: 2 givenname: Chukwuemeka surname: Anene-Nzelu middlename: George fullname: Anene-Nzelu, Chukwuemeka George – sequence: 3 givenname: Manuel surname: Rosa-Garrido fullname: Rosa-Garrido, Manuel – sequence: 4 givenname: Thomas surname: Vondriska middlename: M. fullname: Vondriska, Thomas M. |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31381426$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNUU1v1DAUtFAR3S78BRRuXFL8kTj2BRQF2i5atRLani3XftkYvHGxk63493i1paKcOPl5PG_e88wZOhnDCAi9I_icEE4-dKtv3e263axurturNmPyHDNJRfMCLUhNq7KqmTxBC4yxLBtG6Sk6S-l7vnLW1K_QKSNMkIryBfr62aUEZnLjtuiGGHY6l0UbzeCmDM8Rij7E4jrswRedjtaFvU5m9joWuRV0gmKj4xam9Bq97LVP8ObxXKLbiy-b7qpc31yuunZdmooLWjbkjkpMci2gBmzBkp7VjPeiroVk0hBsOamstqLXoqdCcEEIFszivqmJZUv08ah7P9_twBoYp6i9uo9up-MvFbRTz19GN6ht2CsuhcSVyALvHwVi-DlDmtTOJQPe6xHCnBSlXMiKiezWEr39e9bTkD8GZoI8EkwMKUXonygEq0NY6nlYGZPqGFbu_fRPr3FT9j8c1nb-vxSqo8JD8BPE9MPPDxDVANpPg8p5Y4ZJU1JMJM7fweUBouw3yRWtGw |
| CitedBy_id | crossref_primary_10_3389_fcvm_2021_806988 crossref_primary_10_1096_fj_202300862R crossref_primary_10_1152_physrev_00037_2019 crossref_primary_10_1093_cvr_cvab319 |
| Cites_doi | 10.1038/s41467-017-02762-z 10.1161/CIRCULATIONAHA.118.036726 10.1016/j.cell.2017.05.004 10.1161/CIRCULATIONAHA.117.029430 10.1371/journal.pgen.1006985 |
| ContentType | Journal Article |
| Copyright | 2019 by the American College of Cardiology Foundation and the American Heart Association, Inc. |
| Copyright_xml | – notice: 2019 by the American College of Cardiology Foundation and the American Heart Association, Inc. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 5PM |
| DOI | 10.1161/CIRCULATIONAHA.119.039287 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Anatomy & Physiology |
| EISSN | 1524-4539 |
| EndPage | 448 |
| ExternalDocumentID | PMC6989048 31381426 10_1161_CIRCULATIONAHA_119_039287 00003017-201908060-00002 |
| Genre | Research Support, Non-U.S. Gov't Journal Article Research Support, N.I.H., Extramural |
| GrantInformation_xml | – fundername: NHLBI NIH HHS grantid: R01 HL115238 – fundername: NHLBI NIH HHS grantid: R01 HL105699 – fundername: NHLBI NIH HHS grantid: R01 HL143058 – fundername: NHLBI NIH HHS grantid: R01 HL129639 |
| GroupedDBID | --- .-D .3C .XZ .Z2 01R 0R~ 0ZK 18M 1J1 29B 2FS 2WC 354 40H 4Q1 4Q2 4Q3 53G 5GY 5RE 5VS 6PF 71W 77Y 7O~ AAAAV AAAXR AAGIX AAHPQ AAIQE AAJCS AAMOA AAMTA AAQKA AARTV AASCR AASOK AASXQ AAUEB AAWTL AAXQO ABASU ABBUW ABDIG ABJNI ABOCM ABPMR ABPXF ABQRW ABVCZ ABXVJ ABXYN ABZAD ABZZY ACDDN ACDOF ACEWG ACGFO ACGFS ACILI ACLDA ACOAL ACRKK ACWDW ACWRI ACXJB ACXNZ ACZKN ADBBV ADCYY ADGGA ADHPY AE3 AE6 AEBDS AENEX AFBFQ AFCHL AFDTB AFEXH AFMBP AFNMH AFSOK AFUWQ AGINI AHMBA AHOMT AHQNM AHQVU AHRYX AHVBC AIJEX AINUH AJCLO AJIOK AJNWD AJZMW AKCTQ AKULP ALKUP ALMA_UNASSIGNED_HOLDINGS ALMTX AMJPA AMKUR AMNEI AOHHW AOQMC ASPBG AVWKF AYCSE AZFZN BAWUL BOYCO BQLVK BYPQX C45 CS3 DIK DIWNM DU5 E3Z EBS EEVPB EJD ERAAH EX3 F2K F2L F2M F2N F5P FCALG GNXGY GQDEL GX1 H0~ HLJTE HZ~ IKREB IKYAY IN~ IPNFZ JF9 JG8 JK3 K-A K-F K8S KD2 KMI KQ8 L-C L7B N9A N~7 N~B O9- OAG OAH OBH OCB ODMTH OGEVE OHH OHYEH OK1 OL1 OLB OLG OLH OLU OLV OLY OLZ OPUJH OVD OVDNE OVIDH OVLEI OVOZU OWBYB OWU OWV OWW OWX OWY OWZ OXXIT P2P PQQKQ RAH RIG RLZ S4R S4S T8P TEORI TR2 TSPGW UPT V2I VVN W2D W3M W8F WH7 WOQ WOW X3V X3W XXN XYM YFH YOC YSK YYM YZZ ZFV ZY1 ~H1 AAFWJ AAYXX CITATION ACIJW AWKKM CGR CUY CVF ECM EIF NPM ODA OJAPA OLW RHF 7X8 ADSXY 5PM |
| ID | FETCH-LOGICAL-c4682-71b29014688e5e0ded1f3536f8558939c10d614dad8fa8f2886811083d0f751d3 |
| ISSN | 0009-7322 1524-4539 |
| IngestDate | Thu Aug 21 18:16:52 EDT 2025 Thu Sep 04 20:02:33 EDT 2025 Wed Feb 19 02:30:27 EST 2025 Thu Apr 24 23:10:12 EDT 2025 Tue Jul 01 04:15:25 EDT 2025 Fri May 16 03:41:59 EDT 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6 |
| Keywords | heart failure epigenomics CCCTC-binding factor chromatin |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c4682-71b29014688e5e0ded1f3536f8558939c10d614dad8fa8f2886811083d0f751d3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.119.039287 |
| PMID | 31381426 |
| PQID | 2268943806 |
| PQPubID | 23479 |
| PageCount | 3 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_6989048 proquest_miscellaneous_2268943806 pubmed_primary_31381426 crossref_primary_10_1161_CIRCULATIONAHA_119_039287 crossref_citationtrail_10_1161_CIRCULATIONAHA_119_039287 wolterskluwer_health_00003017-201908060-00002 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2019-August-06 |
| PublicationDateYYYYMMDD | 2019-08-06 |
| PublicationDate_xml | – month: 08 year: 2019 text: 2019-August-06 day: 06 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Circulation (New York, N.Y.) |
| PublicationTitleAlternate | Circulation |
| PublicationYear | 2019 |
| Publisher | by the American College of Cardiology Foundation and the American Heart Association, Inc |
| Publisher_xml | – name: by the American College of Cardiology Foundation and the American Heart Association, Inc |
| References | e_1_3_3_6_2 e_1_3_3_5_2 e_1_3_3_2_2 e_1_3_3_4_2 e_1_3_3_3_2 |
| References_xml | – ident: e_1_3_3_4_2 doi: 10.1038/s41467-017-02762-z – ident: e_1_3_3_3_2 doi: 10.1161/CIRCULATIONAHA.118.036726 – ident: e_1_3_3_6_2 doi: 10.1016/j.cell.2017.05.004 – ident: e_1_3_3_2_2 doi: 10.1161/CIRCULATIONAHA.117.029430 – ident: e_1_3_3_5_2 doi: 10.1371/journal.pgen.1006985 |
| SSID | ssj0006375 |
| Score | 2.3376594 |
| SecondaryResourceType | review_article |
| Snippet | Unraveling the principles of cardiac chromatin organization for next generation therapies in heart disease |
| SourceID | pubmedcentral proquest pubmed crossref wolterskluwer |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 446 |
| SubjectTerms | Animals Aorta Cardiovascular Agents - pharmacology Cardiovascular Agents - therapeutic use Cardiovascular Diseases - drug therapy Cardiovascular Diseases - genetics Cardiovascular Diseases - pathology CCCTC-Binding Factor - deficiency CCCTC-Binding Factor - physiology Chromatin - ultrastructure Chromatin Assembly and Disassembly - drug effects Constriction Disease Models, Animal Drug Design Enhancer Elements, Genetic Epigenesis, Genetic - drug effects Humans Mice Mice, Knockout Molecular Targeted Therapy Myocytes, Cardiac - metabolism Myocytes, Cardiac - ultrastructure Polymorphism, Single Nucleotide Transcription, Genetic - drug effects |
| Title | Dissecting Chromatin Architecture for Novel Cardiovascular Disease Targets |
| URI | https://ovidsp.ovid.com/ovidweb.cgi?T=JS&NEWS=n&CSC=Y&PAGE=fulltext&D=ovft&AN=00003017-201908060-00002 https://www.ncbi.nlm.nih.gov/pubmed/31381426 https://www.proquest.com/docview/2268943806 https://pubmed.ncbi.nlm.nih.gov/PMC6989048 |
| Volume | 140 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3fi9NAEF7qCYcgond61l_kQHw5ciabZLN5LL2rvbNW0FbqU8iPDZb2EmkbD--vd2Z3mya0QvUllG2TLJ0vk5mdb74l5K2FIm-JhRbAMiMPfDNm1DYTmrhURIHlJZLlO2T9sXs98SatVp21VK7i8-RuZ1_J_1gVxsCu2CX7D5atLgoD8BnsC0ewMBz3svEFFtMTSVxGkVsMPvOzTr00gCTCYfFLzJHZUSeeXqjCzNlIMsGX9Ri1O10kelOvXXv11NYOekWh2NnYOvx1OjO_TyusdXLwoubwTsxLVdYvZ7eluBGzSK_Db0o9y8j8EC0W07RQ3UN5KSrex7ciT5H-Hm3YTHoBVy9VYHcUNy1W967UNV1PqRedix1ja5esJJw09uoO1lULltuOn6Hj71596Y4HSka434FRVLANqH6lN8S2h5_D3ngwCEeXk9E9cp_6vqryX32sXuTMkTrN1QwPyam-1fu_3qgZ3mzlLNvU24e3BdIiljPZFVGLbUaPySOdlBgdhbAnpCXyI3LcyaNVcfPbeGdImrCsvxyRw0-ajXFMrjf4Myr8GXX8GYA_Q-LPaOLP0PgzNP6eknHvctTtm3pvDjNxGSZldiwr8Ixz4QkrFamdOZ7DMu55EAIHiW2lEPmlUcqziGeUc8ax48RJrcz37NR5Rg7yIhfPiRFBzu_EHvWjjLuC-UFqJ8LhlGP4nzLWJnz9l4aJFq7H_VPmoUxgmR02rQFjQais0Sa0OvWnUm_Z56TTtd1C8LVYQItyUZTLEFIV3K6AWzCnE2XH6rKODbEvhLtt4jcsXP0Addyb3-TTH1LPHfdwhRdpm5gNLISqExrpIbhu4Zv4SEGCx6QUhEVf7DHPl-TB5kF8RQ5Wi1K8hih6Fb-RWP8Dk4XCPA |
| linkProvider | Flying Publisher |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Dissecting+Chromatin+Architecture+for+Novel+Cardiovascular+Disease+Targets&rft.jtitle=Circulation+%28New+York%2C+N.Y.%29&rft.au=Foo%2C+Roger+Sik-Yin&rft.au=Anene-Nzelu%2C+Chukwuemeka+George&rft.au=Rosa-Garrido%2C+Manuel&rft.au=Vondriska%2C+Thomas+M&rft.date=2019-08-06&rft.issn=1524-4539&rft.eissn=1524-4539&rft.volume=140&rft.issue=6&rft.spage=446&rft_id=info:doi/10.1161%2FCIRCULATIONAHA.119.039287&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0009-7322&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0009-7322&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0009-7322&client=summon |