Dissecting Chromatin Architecture for Novel Cardiovascular Disease Targets

Unraveling the principles of cardiac chromatin organization for next generation therapies in heart disease

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Bibliographic Details
Published inCirculation (New York, N.Y.) Vol. 140; no. 6; pp. 446 - 448
Main Authors Foo, Roger Sik-Yin, Anene-Nzelu, Chukwuemeka George, Rosa-Garrido, Manuel, Vondriska, Thomas M.
Format Journal Article
LanguageEnglish
Published United States by the American College of Cardiology Foundation and the American Heart Association, Inc 06.08.2019
Subjects
Animals
Aorta
Cardiovascular Agents - pharmacology
Cardiovascular Agents - therapeutic use
Cardiovascular Diseases - drug therapy
Cardiovascular Diseases - genetics
Cardiovascular Diseases - pathology
CCCTC-Binding Factor - deficiency
CCCTC-Binding Factor - physiology
Chromatin - ultrastructure
Chromatin Assembly and Disassembly - drug effects
Constriction
Disease Models, Animal
Drug Design
Enhancer Elements, Genetic
Epigenesis, Genetic - drug effects
Humans
Mice
Mice, Knockout
Molecular Targeted Therapy
Myocytes, Cardiac - metabolism
Myocytes, Cardiac - ultrastructure
Polymorphism, Single Nucleotide
Transcription, Genetic - drug effects
heart failure
epigenomics
CCCTC-binding factor
chromatin
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ISSN0009-7322
1524-4539
1524-4539
DOI10.1161/CIRCULATIONAHA.119.039287

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Summary:Unraveling the principles of cardiac chromatin organization for next generation therapies in heart disease
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0009-7322
1524-4539
1524-4539
DOI:10.1161/CIRCULATIONAHA.119.039287