Diagnostic and therapeutic guidelines for plaque psoriasis - Brazilian Society of Dermatology

• Published in: Anais brasileiros de dermatología Vol. 94; no. 2 Suppl 1; pp. 76 - 107
• Main Authors: Arnone, Marcelo, Takahashi, Maria Denise Fonseca, Carvalho, André Vicente Esteves de, Bernardo, Wanderley Marques, Bressan, Aline Lopes, Ramos, Andrea Machado Coelho, Terena, Aripuanã Cobério, Souza, Cacilda da Silva, Nunes, Daniel Holthausen, Bortoletto, Maria Cecília de Carvalho, Oliveira, Maria de Fátima Santos Paim de, Neffá, Jane Marcy, Fieri, Luciana Cristina, Azulay-Abulafia, Luna, Felix, Paulo Antônio Oldani, Magalhaes, Renata Ferreira, Romiti, Ricardo, Jaime, Tatiana Jerez
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil Sociedade Brasileira de Dermatologia 01.04.2019
• Subjects: Adrenal Cortex Hormones - therapeutic use; Anthralin - therapeutic use; Antibodies, Monoclonal - therapeutic use; Biological therapy; Brazil; Calcineurin Inhibitors - therapeutic use; Comorbidity; Cyclosporine - therapeutic use; Dermatologic Agents - therapeutic use; DERMATOLOGY; Drug Combinations; Female; Humans; Male; Methotrexate - therapeutic use; Phototherapy - methods; Practice guidelines as topic; Psoriasis; Psoriasis - diagnosis; Psoriasis - epidemiology; Psoriasis - therapy; Severity of Illness Index; Societies, Medical; Time Factors; Vitamin D - analysis; Brazil; Biological therapy; Psoriasis; Practice guidelines as topic; Comorbidity; Dermatology
• ISSN: 0365-0596; 1806-4841; 1806-4841
• DOI: 10.1590/abd1806-4841.2019940211

Psoriasis is a chronic inflammatory disease that affects 1.3% of the Brazilian population. The most common clinical manifestations are erythematous, scaling lesions that affect both genders and can occur on any anatomical site, preferentially involving the knees, elbows, scalp and genitals. Besides the impact on the quality of life, the systemic nature of the disease makes psoriasis an independent risk factor for cardiovascular disease, especially in young patients with severe disease. By an initiative of the Brazilian Society of Dermatology, dermatologists with renowned clinical experience in the management of psoriasis were invited to form a work group that, in a partnership with the Brazilian Medical Association, dedicated themselves to create the Plaque Psoriasis Diagnostic and Treatment Guidelines. The relevant issues for the diagnosis (evaluation of severity and comorbidities) and treatment of plaque psoriasis were defined. The issues generated a search strategy in the Medline-PubMed database up to July 2018. Subsequently, the answers to the questions of the recommendations were devised, and each reference selected presented the respective level of recommendation and strength of scientific evidence. The final recommendations for making up the final text were worded by the coordinators.