Lack of effect of intravenous metformin on plasma concentrations of glucose, insulin, C-peptide, glucagon and growth hormone in non-diabetic subjects

• Published in: Current medical research and opinion Vol. 9; no. 1; p. 47
• Main Authors: Bonora, E, Cigolini, M, Bosello, O, Zancanaro, C, Capretti, L, Zavaroni, I, Coscelli, C, Butturini, U
• Format: Journal Article
• Language: English
• Published: England 1984
• Subjects: Adult; Blood Glucose - metabolism; C-Peptide - blood; Female; Glucagon - blood; Growth Hormone - blood; Humans; Injections, Intravenous; Insulin - blood; Male; Metformin - administration & dosage; Metformin - pharmacology; Middle Aged

A study was carried out to evaluate the acute effect of an intravenous injection of metformin on the fasting plasma concentrations of glucose, insulin, C-peptide, glucagon and growth hormone in 15 non-diabetic subjects. Metformin (1 g) was administered as a bolus in a peripheral vein and blood was s...