Hormonal responses to consecutive days of heavy-resistance exercise with or without nutritional supplementation

• Published in: Journal of applied physiology (1985) Vol. 85; no. 4; pp. 1544 - 1555
• Main Authors: Kraemer, William J, Volek, Jeff S, Bush, Jill A, Putukian, Margot, Sebastianelli, Wayne J
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Am Physiological Soc 01.10.1998; American Physiological Society
• Subjects: Adult; Anatomy & physiology; Biological and medical sciences; Body Composition; Comparative studies; Cross-Over Studies; Dietary Carbohydrates; Dietary Proteins; Dietary supplements; Double-Blind Method; Effects; Energy Intake; Exercise; Food, Fortified; Fundamental and applied biological sciences. Psychology; Hormones; Hormones - blood; Human Growth Hormone - blood; Humans; Hydrocortisone - blood; Insulin - blood; Insulin-Like Growth Factor I - metabolism; Male; Physical Endurance; Prolactin - blood; Sex Hormone-Binding Globulin - metabolism; Testosterone - blood; Time Factors; Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports; Weight Lifting - physiology; Physical exercise; Human; Physical training; Androgen; Intensity; Somatotropin hormone; Insulin like growth factor 1; Protein; Feeding; Testosterone; Adenohypophyseal hormone; Hormonal regulation; Carbohydrate; High calorie diet; Testicular hormone; Supplementation; Sex steroid hormone
• ISSN: 8750-7587; 1522-1601
• DOI: 10.1152/jappl.1998.85.4.1544

1  Laboratory for Sports Medicine, Department of Kinesiology, and 2  Center for Sports Medicine, The Pennsylvania State University, University Park, Pennsylvania 16802; and 3  The Human Performance Laboratory, Ball State University, Muncie, Indiana 47306 Nine resistance-trained men consumed either a protein-carbohydrate supplement or placebo for 1 wk in a crossover design separated by 7 days. The last 3 days of each treatment, subjects performed resistance exercise. The supplement was consumed 2 h before and immediately after the workout, and blood was obtained before and after exercise (0, 15, 30, 45, and 60 min postexercise). Lactate, growth hormone, and testosterone were significantly ( P    0.05) elevated immediately postexercise. The lactate response was significantly lower during supplementation on days 2  and 3 . Growth hormone and prolactin responses on day 1  were significantly higher during supplementation. After exercise, testosterone declined below resting values during supplementation. Cortisol decreased immediately postexercise on day 1 ; the response was diminished on days 2  and 3 . Glucose and insulin were significantly elevated by 30 min during supplementation and remained stable during placebo. Insulin-like growth factor-I was higher during supplementatiom on days 2  and 3 . These data indicate that protein-carbohydrate supplementation before and after training can alter the metabolic and hormonal responses to consecutive days of heavy-resistance exercise. testosterone; growth hormone; insulin; insulin-like growth factor-I; protein; carbohydrate; anabolic; weight training