Determination of Ciprofloxacin by Flow Injection Analysis Based on Chemiluminescence System

• Published in: Journal of rare earths Vol. 24; no. 3; pp. 285 - 288
• Main Author: 张卓勇 李夏 王小丽 陈世稆 宋保华 赵慧春
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.06.2006; Department of Chemistry, Capital Normal University, Beijing 100037, China%Department of Chemistry, Beijing Normal University, Beijing 100875, China
• Subjects: chemiluminescence; ciprofloxacin; flow injection; KMnO 4; KMnO4; Na 2S 2O 4; Na2S2O4; P595; rare earths; terbium; 化学发光; 流动注射; 环丙沙星; terbium; P595; chemiluminescence; flow injection; Na 2S 2O 4; KMnO 4; ciprofloxacin; rare earths; Na2S2O4; KMnO4
• ISSN: 1002-0721; 2509-4963
• DOI: 10.1016/s1002-0721(06)60110-5

A novel flow injection chemiluminescence （CL） method for the determination of ciprofloxacin （CPLX） was reported. The proposed method is based on luminescence produced by KMnO4-Na2S2O4-Tb^3＋-CPLX chemiluminescence （CL） system. The effects of some critical experimental conditions were discussed and the optimization of working conditions was investigated. The linear dynamic range is 3.00 × 10^-8 - 9.00 × 10^-7 mol ·L-1 and the detection limit for CPLX is 4.40 × 10^-9 mol·L^-1. This method was applied to the determination of CPLX in tablet, urine, and serum samples and the recoveries of real sample analyses were in the range from 110 ± 4 to 104 ± 4.