A Novel Quantitative Spasticity Evaluation Method Based on Surface Electromyogram Signals and Adaptive Neuro Fuzzy Inference System

• Published in: Frontiers in neuroscience Vol. 14; p. 462
• Main Authors: Yu, Song, Chen, Yan, Cai, Qing, Ma, Ke, Zheng, Haiqing, Xie, Longhan
• Format: Journal Article
• Language: English
• Published: Lausanne Frontiers Research Foundation 25.05.2020; Frontiers Media S.A
• Subjects: ANFIS; Elbow; Electrodes; Electromyography; Experiments; Magnetic fields; Methods; Modified Ashworth scale; Neural networks; Neuroscience; Patients; Rehabilitation; Spasticity; spasticity assessment; Stretch reflex; Stretching; Stroke; surface electromyogram; Therapists; Transcranial magnetic stimulation
• ISSN: 1662-453X; 1662-4548; 1662-453X
• DOI: 10.3389/fnins.2020.00462

Stroke patients often suffer from spasticity. Before treatment of spasticity, there are often practical demands for objective and quantitative assessment of muscle spasticity. However, the common quantitative spasticity assessment method, the tonic stretch reflex threshold (TSRT), is time-consuming and complicated to implement due to the requirement of multiple passive stretches. To evaluate spasticity conveniently, a novel spasticity evaluation method based on surface electromyogram (sEMG) signals and adaptive neuro fuzzy inference system (i.e., the sEMG-ANFIS method) was presented in this paper. Eleven stroke patients with spasticity and 4 healthy subjects were recruited to participate in the experiment. During the experiment, the Modified Ashworth scale (MAS) scores of each subject was obtained and sEMG signals from four elbow flexors or extensors were collected from several times (4-5) repetitions of passive stretching. Four time-domain features (root mean square, the zero-cross rate, the wavelength and a 4th-order autoregressive model coefficient) and one frequency-domain feature (the mean power frequency) were extracted from the collected sEMG signals to reflect the spasticity information. Using the ANFIS classifier, excellent regression performance was achieved (mean accuracy = 0.96, mean root-mean-square error (RMSE) = 0.13), outperforming the classical TSRT method (accuracy = 0.88, RMSE = 0.28). The results showed that the sEMG-ANFIS method not only has higher accuracy but also is convenient to implement by requiring fewer repetitions (4-5) of passive stretches. The sEMG-ANFIS method can help stroke patients develop proper rehabilitation training programs and can potentially be used to provide therapeutic feedback for some new spasticity interventions, such as shockwave therapy and repetitive transcranial magnetic stimulation.