Influence of data processing on cyclic variation of integrated backscatter and wall thickness in stunned porcine myocardium

• Published in: Ultrasound in medicine & biology Vol. 23; no. 3; pp. 405 - 414
• Main Authors: van der Steen, Anton F.W., Rijsterborgh, Hans, Lancée, Charles T., Mastik, Frits, Krams, Rob, Verdouw, Pieter D., Roelandt, Jos R.T.C., Bom, Nicolaas
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Inc 1997; Elsevier
• Subjects: Animals; Biological and medical sciences; Cardiovascular system; Cyclic variation; Data processing; Echocardiography - methods; Electronic Data Processing; Female; Fourier Analysis; Integrated backscatter; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Myocardial Stunning - diagnostic imaging; Periodicity; Scattering, Radiation; Stunned myocardium; Swine; Transducers; Ultrasonic investigative techniques; Wall thickening; Integrated backscatter; Wall thickening; Data processing; Cyclic variation; Stunned myocardium; Sonography; Energy spectrum; Data analysis; Correlation; Backscattering; Wall thickness; Experimental study; Pig; Periodic variation; Vertebrata; Mammalia; Cardiac cycle; Animal; Myocardium; Artiodactyla; Circulatory system; Technique; Ungulata
• ISSN: 0301-5629; 1879-291X
• DOI: 10.1016/S0301-5629(96)00227-X

This study was performed to investigate the relationship between the cyclic variation of integrated backscatter and myocardial wall thickening in stunned myocardium. Different definitions of cyclic variation were evaluated to be able to compare with other studies. Ultrasound data were acquired from 10 openchested Yorkshire pigs (25–33 kg) at baseline, during regional ischemia and during 30 min of stunning, using a broadband ultrasound transducer (3–7 MHz) sutured directly upon the left ventricular myocardial wall. Cyclic variation of integrated backscatter and myocardial wall thickening were calculated using three definitions obtained from the literature. Independent of the definition, cyclic variation of wall thickness and integrated backscatter were blunted during acute ischemia and returned transiently to or above baseline during the first minute of reperfusion, followed by a gradual decrease to a level under baseline during stunning. An early return of the cyclic variation of the integrated backscatter was not observed in pigs, independent of the data processing used. The relationship between integrated backscatter and wall thickness was maintained.