Familial cardiac myxoma

• Published in: The Annals of thoracic surgery Vol. 53; no. 3; pp. 419 - 424
• Main Authors: Van Gelder, Hugh M., O'Brien, Daniel J., Staples, Edward D., Alexander, James A.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.03.1992; Elsevier Science
• Subjects: Adolescent; Adult; Biological and medical sciences; Cardiology. Vascular system; Child; Echocardiography; Female; Heart; Heart Atria; Heart Neoplasms - diagnostic imaging; Heart Neoplasms - genetics; Humans; Male; Medical sciences; Middle Aged; Myxoma - diagnostic imaging; Myxoma - genetics; Tumors of the heart; Heart; Case study; Human; Myxoma; Family study; Heart disease; Cardiovascular disease; Benign neoplasm
• ISSN: 0003-4975; 1552-6259
• DOI: 10.1016/0003-4975(92)90261-2

The majority of cardiac myxomas occur sporadically as isolated lesions in the left atrium of middle-aged women. However, a “familial” form and a “syndrome” form of this lesion have been identified. The syndrome myxoma can present with pigmented skin lesions and peripheral or endocrine neoplasms. The familial and syndrome forms of cardiac myxomas can usually be distinguished from the sporadic form by the presentation at a younger age, the unusual location and multicentricity of the lesions, and the presence of rare pathological conditions. In addition, a higher rate of recurrent lesions is usually associated with the familial and syndrome forms of this disease. To date, 15 families with cardiac myxomas have been reported in the world's literature. Here we present 2 additional case reports.