Effects of galvanic mastoid stimulation in seated human subjects

• Published in: Journal of applied physiology (1985) Vol. 106; no. 3; pp. 893 - 903
• Main Authors: Ghanim, Z, Lamy, J. C, Lackmy, A, Achache, V, Roche, N, Penicaud, A, Meunier, S, Katz, R
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Am Physiological Soc 01.03.2009; American Physiological Society
• Subjects: Adult; Anesthetics, Local - administration & dosage; Biological and medical sciences; Comparative analysis; Effects; Electric Stimulation; Electromyography - methods; Female; Fundamental and applied biological sciences. Psychology; Habituation, Psychophysiologic - physiology; Humans; Isometric Contraction - physiology; Leg; Male; Mastoid; Middle Aged; Muscle, Skeletal - physiology; Musculoskeletal system; Posture - physiology; Proprioception - physiology; Reflex, Monosynaptic - physiology; Reflexes; Skin - drug effects; Studies; Vestibule, Labyrinth - physiology; Young Adult; Human; H and T reflexes; Vertebrata; sensory afferents; Mammalia; startle pattern; H-Reflex; vestibular afferents; Stimulation; galvanic stimulation; humans
• ISSN: 8750-7587; 1522-1601
• DOI: 10.1152/japplphysiol.90594.2008

1 Université Pierre et Marie Curie-Paris 6, Unité Mixte de Recherche, Paris; 2 Institut National de la Santé et de la Recherche Médicale, U 731, Paris; 3 Service de Médecine Physique et Réadaptation, Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière, Paris; 4 Service de Médecine Physique et Réadaptation, Assistance Publique-Hôpitaux de Paris, Raymond Poincaré Hospital, Garches; 5 National Hospital, Saint Maurice France; and 6 Department of Functional Investigation Assistance Publique-Hôpitaux de Paris, Tenon Hospital, Paris France Submitted 30 April 2008 ; accepted in final form 13 December 2008 The vestibular responses evoked by transmastoid galvanic stimulation (GS) in the rectified soleus electromyogram (EMG) in freely standing human subjects disappear when seated. However, a GS-induced facilitation of the soleus monosynaptic (H and tendon jerk) reflex has been described in few experiments in subjects lying prone or seated. This study addresses the issue of whether this reflex facilitation while seated is of vestibulospinal origin. GS-induced responses in the soleus (modulation of the rectified ongoing EMG and of the monosynaptic reflexes) were compared in the same normal subjects while freely standing and sitting with back and head support. The polarity-dependent biphasic responses in the free-standing position were replaced by a non-polarity-dependent twofold facilitation while seated. The effects of GS were hardly detectable in the rectified ongoing voluntary EMG activity, weak for the H reflex, but large and constant for the tendon jerk. They were subject to habituation. Anesthesia of the skin beneath the GS electrodes markedly reduced the reflex facilitation, while a similar, although weaker, facilitation of the tendon jerk was observed when GS was replaced with purely cutaneous stimulation, a tap to the tendon of the sternomastoid muscle, or an auditory click. The stimulation polarity independence of the GS-induced reflex facilitation argues strongly against a vestibular response. However, the vestibular afferent volley, insufficient to produce a vestibular reflex response while seated, could summate with the GS-induced tactile or proprioceptive volley to produce a startle-like response responsible for the reflex facilitation. vestibular afferents; sensory afferents; H and T reflexes; startle pattern; galvanic stimulation; humans Address for reprint requests and other correspondence: R. Katz, UMRS 731 INSERM, Univ Paris 06, Médecine Physique et Réadaptation, Hôpital de la Salpêtrière, 75651 Paris cedex 13, France (e-mail: rose.katz{at}upmc.fr )