Re-emergence of another vaccine-preventable disease?—Two cases of rubella in older adults

Abstract Unlike its devastating teratogenic effects, post-natal infection with rubella typically causes subclinical or inapparent illness. While rubella has been largely eliminated from the United States following the introduction of an efficacious live-attenuated vaccine in 1969, a small proportion...

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Bibliographic Details
Published inJournal of clinical virology Vol. 46; no. 1; pp. 98 - 100
Main Authors Louie, Janice K, Shaikh-Laskos, Rina, Preas, Christopher, Nguyen, Vi T, Peters, Anne, Messenger, Sharon
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier B.V 01.09.2009
Elsevier
Subjects
Adult
Allergy and Immunology
Biological and medical sciences
Communicable Diseases, Emerging - epidemiology
Febrile rash
Female
Fundamental and applied biological sciences. Psychology
Human viral diseases
Humans
Incidence
Infectious Disease
Infectious diseases
Measles
Medical sciences
Microbiology
Middle Aged
Miscellaneous
Rubella
Rubella - diagnosis
Rubella - epidemiology
Rubella Vaccine - immunology
United States - epidemiology
Vaccination - utilization
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies
Viral diseases
Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye
Virology
United States
Rubella
Measles
Febrile rash
Human
Infection
Microbiology
Viral disease
Vaccine
Elderly
Virology
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Summary:Abstract Unlike its devastating teratogenic effects, post-natal infection with rubella typically causes subclinical or inapparent illness. While rubella has been largely eliminated from the United States following the introduction of an efficacious live-attenuated vaccine in 1969, a small proportion of the population remains susceptible. Recent declining vaccination rates have resulted in a rising incidence of sporadic and outbreak-associated measles, reminding us that an increasing proportion of the population is also susceptible to, and may be reservoirs of transmission for, rubella. We describe two rare adult cases with no clear exposure. These cases serve as a reminder that clinicians should remain vigilant and consider rubella infection in susceptible patients, including older adults, presenting with febrile rash illness.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1386-6532
1873-5967
DOI:10.1016/j.jcv.2009.06.013