Primary cutaneous Ewing’s sarcoma/primitive neuroectodermal tumor manifesting numerous small and huge ulcerated masses: its complete remission by chemotherapy and magnetic resonance imaging findings

• Published in: Skeletal radiology Vol. 39; no. 6; pp. 595 - 600
• Main Authors: Bahk, Won-Jong, Chang, Eun-Deok, Bae, Jung Min, Chun, Kyung-Ah, Lee, An-Hee, Rho, Sang-Young, Kim, Jin Woo
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.06.2010; Springer; Springer Nature B.V
• Subjects: Antineoplastic Agents - administration & dosage; Biological and medical sciences; Cancer; Case Report; Chemotherapy; Diseases of the osteoarticular system; Humans; Imaging; Investigative techniques, diagnostic techniques (general aspects); Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Medical sciences; Medicine; Medicine & Public Health; Middle Aged; Neoplasms, Multiple Primary - complications; Neoplasms, Multiple Primary - diagnosis; Neoplasms, Multiple Primary - drug therapy; Neuroectodermal Tumors - complications; Neuroectodermal Tumors - diagnosis; Neuroectodermal Tumors - drug therapy; Nuclear Medicine; Orthopedics; Osteoarticular system. Muscles; Pathology; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Radiology; Sarcoma; Sarcoma, Ewing - complications; Sarcoma, Ewing - diagnosis; Sarcoma, Ewing - drug therapy; Skin Neoplasms - complications; Skin Neoplasms - diagnosis; Skin Neoplasms - drug therapy; Treatment Outcome; Tumors of striated muscle and skeleton; Ulcer - diagnosis; Ulcer - etiology; Ulcer - prevention & control; Vincristine; Multiple huge masses; Clinical outcome; MRI findings; Primary cutaneous Ewing’s sarcoma/primitive neuroectodermal tumor; Nuclear medicine; Primary cutaneous Ewing's sarcoma/primitive neuroectodermal tumor; Ewing sarcoma; Multiple; Prognosis; Diseases of the osteoarticular system; Malignant tumor; Nuclear magnetic resonance imaging; Neuroectodermal tumor; Chemotherapy; Primitive; Treatment; Orthopedics; Medical imagery; Remission; Skin; Ulceration; Cancer
• ISSN: 0364-2348; 1432-2161
• DOI: 10.1007/s00256-009-0872-x

Extraskeletal Ewing’s sarcoma (ES) and primitive neuroectodermal tumor (PNET) are widely regarded as clinically and histologically identical tumors which consist of small blue round cells. Extraskeletal ESs/PNETs usually occur in the deep soft tissues of the paraspinal region, chest wall, or lower extremities. However, superficially located cases, so-called cutaneous ESs/PNETs, are exceedingly rare, and the vast majority of the reported cases present as a single small mass. We present magnetic resonance imaging (MRI) findings and clinical course of a unique case of primary cutaneous ES/PNET presenting as numerous huge masses with severe ulceration on them.