Treatment of Acute Coronary Syndromes
To the Editor: The results of the Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) study (Aug. 16 issue) 1 suggest that the addition of clopidogrel to aspirin is beneficial for patients who have acute coronary syndromes without elevation of the ST segment. The inclusion criteria wer...
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Published in | The New England journal of medicine Vol. 346; no. 3; pp. 206 - 208 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
United States
Massachusetts Medical Society
17.01.2002
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Subjects | |
Online Access | Get full text |
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Summary: | To the Editor:
The results of the Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) study (Aug. 16 issue)
1
suggest that the addition of clopidogrel to aspirin is beneficial for patients who have acute coronary syndromes without elevation of the ST segment. The inclusion criteria were changed after the first 3000 patients had been recruited. This change in the entry criteria during the course of recruitment means that the analysis of the results could be interpreted as a meta-analysis of two separate studies, rather than a single study. If one takes this view, the findings necessarily carry less weight. . . . |
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Bibliography: | SourceType-Other Sources-1 content type line 63 ObjectType-Correspondence-1 ObjectType-Commentary-2 |
ISSN: | 0028-4793 1533-4406 |
DOI: | 10.1056/NEJM200201173460313 |