Expression of enhancer binding factors associated with various cell types of lung cancer

• Published in: Biochemical and biophysical research communications Vol. 180; no. 2; pp. 1064 - 1069
• Main Authors: Wong, Yuk-Chor, Bernal, Samuel D.
• Format: Journal Article
• Language: English
• Published: San Diego, CA Elsevier Inc 31.10.1991; Elsevier
• Subjects: Adenocarcinoma - genetics; Base Sequence; Binding Sites; Biological and medical sciences; Carcinoma - genetics; Cell Line; DNA-Binding Proteins - genetics; Enhancer Elements, Genetic; Host-tumor relations. Immunology. Biological markers; Humans; Lung Neoplasms - genetics; Medical sciences; Molecular Sequence Data; Nuclear Proteins - metabolism; Oligodeoxyribonucleotides; Proto-Oncogene Proteins c-jun - genetics; Transcription Factors - genetics; Transcription Factors - metabolism; Tumors; Human; Cell culture; Enhancer sequence; Carcinoma; Type specificity; Lung; Tumor; Molecular probe; Gene expression

Differential expression of nuclear factors binding specifically to AP-1, AP-2, AP-3, and NF-I/CTF enhancer elements was found in the various cell types of human lung carcinoma cells. Adenocarcinoma and squamous carcinoma cells seemed to express higher levels of these factors than large-cell carcinom...