Predictive modeling and in vivo assessment of cerebral blood flow in the management of complex cerebral aneurysms

Cerebral aneurysms are weakened blood vessel dilatations that can result in spontaneous, devastating hemorrhage events. Aneurysm treatment aims to reduce hemorrhage events, and strategies for complex aneurysms often require surgical bypass or endovascular stenting for blood flow diversion. Intervent...

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Published inJournal of cerebral blood flow and metabolism Vol. 36; no. 6; pp. 998 - 1003
Main Authors Walcott, Brian P, Reinshagen, Clemens, Stapleton, Christopher J, Choudhri, Omar, Rayz, Vitaliy, Saloner, David, Lawton, Michael T
Format Journal Article
LanguageEnglish
Published London, England SAGE Publications 01.06.2016
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ISSN0271-678X
1559-7016
DOI10.1177/0271678X16641125

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Summary:Cerebral aneurysms are weakened blood vessel dilatations that can result in spontaneous, devastating hemorrhage events. Aneurysm treatment aims to reduce hemorrhage events, and strategies for complex aneurysms often require surgical bypass or endovascular stenting for blood flow diversion. Interventions that divert blood flow from their normal circulation patterns have the potential to result in unintentional ischemia. Recent developments in computational modeling and in vivo assessment of hemodynamics for cerebral aneurysm treatment have entered into clinical practice. Herein, we review how these techniques are currently utilized to improve risk stratification and treatment planning.
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Brian P Walcott and Clemens Reinshagen made equal contribution.
ISSN:0271-678X
1559-7016
DOI:10.1177/0271678X16641125