Study of HLA antigens in systemic lupus erythematosus in the French West Indies

As incidence of SLE is high in Blacks, we studied HLA and SLE associations in the French West Indies, whose population is racially mixed. Forty-seven coloured SLE patients have been typed in HLA A,B,C and DR. We observed B8 association in nearly all of the studies. B15 association, more frequent in...

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Bibliographic Details
Published inTissue antigens Vol. 31; no. 5; p. 238
Main Authors Monplaisir, N, Valette, I, Pierre-Louis, S, Yoyo, M, Sobesky, G, Verpré, F C, Quist, D, Arfi, S, Gervaise, G, Gabriel, J M
Format Journal Article
LanguageEnglish
Published England 01.05.1988
Subjects
HLA Antigens - analysis
HLA Antigens - genetics
HLA-D Antigens - analysis
HLA-DR Antigens - analysis
HLA-DR Antigens - genetics
Humans
Lupus Erythematosus, Systemic - genetics
Lupus Erythematosus, Systemic - immunology
West Indies
West Indies
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Summary:As incidence of SLE is high in Blacks, we studied HLA and SLE associations in the French West Indies, whose population is racially mixed. Forty-seven coloured SLE patients have been typed in HLA A,B,C and DR. We observed B8 association in nearly all of the studies. B15 association, more frequent in Caucasians, was found, also B53 association, a Black variant of B5 more frequent in Blacks. We did not find any class II association.
ISSN:0001-2815
DOI:10.1111/j.1399-0039.1988.tb02089.x