New weapons to fight malaria transmission: A historical view

The stagnation of our fight against malaria in recent years, mainly due to the development of mosquito insecticide resistance, argues for the urgent development of new weapons. The dramatic evolution of molecular tools in the last few decades led to a better understanding of parasite–mosquito intera...

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Published inEntomological research Vol. 52; no. 5; pp. 235 - 240
Main Authors Huang, Wei, Cha, Sung‐Jae, Jacobs‐Lorena, Marcelo
Format Journal Article
LanguageEnglish
Published Korea (South) Wiley Subscription Services, Inc 01.05.2022
John Wiley and Sons Inc
Subjects
Biology, Ecology and Behavior
Disease transmission
Disease transmission and blood feeding arthropods
Malaria
Malaria transmission
Medical and Veterinary Entomology
Mosquitoes
Pesticide resistance
Review
Symbiotic relationships
Malaria transmission
Disease transmission and blood feeding arthropods
Medical and Veterinary Entomology
Symbiotic relationships
Biology, Ecology and Behavior
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Summary:The stagnation of our fight against malaria in recent years, mainly due to the development of mosquito insecticide resistance, argues for the urgent development of new weapons. The dramatic evolution of molecular tools in the last few decades led to a better understanding of parasite–mosquito interactions and coalesced in the development of novel tools namely, mosquito transgenesis and paratransgenesis. Here we provide a historical view of the development of these new tools and point to some remaining challenges for their implementation in the field.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1738-2297
1748-5967
DOI:10.1111/1748-5967.12585