Deep, Dark Secrets of Melatonin in Animal Evolution

Tosches et al. show that melatonin signaling regulates circadian swimming in annelid worms by rhythmically activating cholinergic neurons. This suggests an evolutionary connection between melatonin signaling in invertebrates and sleep regulation in vertebrates. Tosches et al. show that melatonin sig...

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Bibliographic Details
Published inCell Vol. 159; no. 1; pp. 9 - 10
Main Authors Schippers, Klaske J., Nichols, Scott A.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 25.09.2014
Subjects
Animals
Melatonin - metabolism
Photoreceptor Cells, Invertebrate - metabolism
Polychaeta - physiology
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Summary:Tosches et al. show that melatonin signaling regulates circadian swimming in annelid worms by rhythmically activating cholinergic neurons. This suggests an evolutionary connection between melatonin signaling in invertebrates and sleep regulation in vertebrates. Tosches et al. show that melatonin signaling regulates circadian swimming in annelid worms by rhythmically activating cholinergic neurons. This suggests an evolutionary connection between melatonin signaling in invertebrates and sleep regulation in vertebrates.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Commentary-1
ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2014.09.004