Theta-Range Oscillations in Stress-Induced Mental Disorders as an Oscillotherapeutic Target

Emotional behavior and psychological disorders are expressed through coordinated interactions across multiple brain regions. Brain electrophysiological signals are composed of diverse neuronal oscillations, representing cell-level to region-level neuronal activity patterns, and serve as a biomarker...

Full description

Saved in:
Bibliographic Details
Published inFrontiers in behavioral neuroscience Vol. 15; p. 698753
Main Authors Okonogi, Toya, Sasaki, Takuya
Format Journal Article
LanguageEnglish
Published Lausanne Frontiers Research Foundation 09.06.2021
Frontiers Media S.A
Subjects
3-D printers
Activity patterns
Amygdala
Animals
Anxiety
Behavior
Behavioral Neuroscience
Brain research
Convulsions & seizures
depression
Electrocardiography
Electrodes
emotion
Emotional behavior
Emotions
Experiments
hippocampus
Mental disorders
oscillations
Physiology
Post traumatic stress disorder
Prefrontal cortex
Rodents
Theta rhythms
Online AccessGet full text

Cover

More Information
Summary:Emotional behavior and psychological disorders are expressed through coordinated interactions across multiple brain regions. Brain electrophysiological signals are composed of diverse neuronal oscillations, representing cell-level to region-level neuronal activity patterns, and serve as a biomarker of mental disorders. Here, we review recent observations from rodents demonstrating how neuronal oscillations in the hippocampus, amygdala, and prefrontal cortex are engaged in emotional behavior and altered by psychiatric changes such as anxiety and depression. In particular, we focus mainly on theta-range (4–12 Hz) oscillations, including several distinct oscillations in this frequency range. We then discuss therapeutic possibilities related to controlling such mental disease-related neuronal oscillations to ameliorate psychiatric symptoms and disorders in rodents and humans.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
This article was submitted to Pathological Conditions, a section of the journal Frontiers in Behavioral Neuroscience
Edited by: Yuichi Takeuchi, Osaka City University, Japan
Reviewed by: Brendon O. Watson, University of Michigan, United States; Thomas John McHugh, RIKEN Brain Science Institute (RIKEN BSI), Japan
ISSN:1662-5153
1662-5153
DOI:10.3389/fnbeh.2021.698753