Decreased tricuspid regurgitation following percutaneous closure of congenital perimembranous ventricular septal defect: immediate and 6-month echocardiographic assessment

• Published in: Heart and vessels Vol. 30; no. 5; pp. 611 - 617
• Main Authors: Xu, Xu-Dong, Liu, Su-Xuan, Bai, Yuan, Zhang, Min, Zhao, Xian-Xian, Qin, Yong-Wen
• Format: Journal Article
• Language: English
• Published: Tokyo Springer Japan 01.09.2015; Springer Nature B.V
• Subjects: Adult; Biomedical Engineering and Bioengineering; Cardiac Catheterization - methods; Cardiac Surgery; Cardiology; Cardiovascular disease; Clinical outcomes; Congenital diseases; Disease Progression; Echocardiography, Doppler, Color - methods; Female; Follow-Up Studies; Heart Septal Defects, Ventricular - complications; Heart Septal Defects, Ventricular - physiopathology; Heart Septal Defects, Ventricular - surgery; Humans; Male; Medical procedures; Medicine; Medicine & Public Health; Middle Aged; Original Article; Postoperative Period; Retrospective Studies; Stroke Volume - physiology; Time Factors; Treatment Outcome; Tricuspid Valve Insufficiency - diagnostic imaging; Tricuspid Valve Insufficiency - etiology; Tricuspid Valve Insufficiency - physiopathology; Ultrasonic imaging; Vascular Surgery; Congenital heart disease; Ventricular septal defect; Transcatheter; Tricuspid regurgitation
• ISSN: 0910-8327; 1615-2573
• DOI: 10.1007/s00380-014-0531-6

As a common concomitant performance and the most frequent complications of transcatheter perimembranous ventricular septal defect (VSD) closure, tricuspid regurgitation (TR) has rarely been concerned. From January 2008 to December 2012, a total of 70 patients (men: 33, women: 37; mean age: 30.0 ± 17.1 years) with at least mild TR before VSD closure were examined in 508 consecutive congenital perimembranous VSD patients to investigate the outcomes of TR. After VSD closure, the jet area decreased from 3.4 ± 2.5 to 1.2 ± 2.5 cm 2 ( p  < 0.001); however, no significant decrease was found in 3 patients (mean age 59.7 ± 2.5 years) with severe TR (12.0 ± 1.2 versus 11.2 ± 3.2 cm 2 , p  = 0.668). Compared to the early outcome after VSD closure, the jet area detected by TTE at 6-month follow-up had further decreased (1.2 ± 2.5 versus 0.9 ± 2.2 cm 2 , p  < 0.001). In 6 patients, a slight residual shunt was detected immediately after VSD closure and diminished in 3 patients at 6-month follow-up. The hemolysis occurred in one of these six patients and recovered after 3 days. In conclusion, functional TR was ameliorated after percutaneous VSD closure, although persistent abundant TR was common in patients with severe TR before procedure.