Mode of action of Buddleja cordata verbascoside against Staphylococcus aureus

We evaluate the mode of action of verbascoside obtained from Buddleja cordata against Staphylococcus aureus by killing kinetics and incorporation of precursors methods. Verbascoside induced lethal effect on S. aureus, by affecting protein synthesis and inhibiting leucine incorporation.

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Bibliographic Details
Published inJournal of ethnopharmacology Vol. 66; no. 1; pp. 75 - 78
Main Authors Guillermo Avila, José, de Liverant, Juliana G., Martı́nez, Andrés, Martı́nez, Gabriel, Muñoz, José Luis, Arciniegas, Amira, Romo de Vivar, Alfonso
Format Journal Article
LanguageEnglish
Published Shannon Elsevier Ireland Ltd 01.07.1999
Elsevier
Subjects
Anti-Bacterial Agents - pharmacology
antibacterial properties
Biological and medical sciences
Buddleja cordata
General pharmacology
Glucosides - pharmacology
Medical sciences
medicinal plants
Microbial Sensitivity Tests
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phenols
Plant Extracts - pharmacology
Plants, Medicinal - chemistry
Radioactive precursor
Staphylococcus aureus
Staphylococcus aureus - drug effects
tepozan
traditional medicine
Verbascoside
Mexico
Verbascoside
Buddleja cordata
Staphylococcus aureus
Radioactive precursor
Buddlejaceae
Pharmacognosy
Dicotyledones
Angiospermae
Plant origin
Spermatophyta
Buddleja
Antibacterial agent
Mechanism of action
In vitro
Biological activity
Medicinal plant
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Summary:We evaluate the mode of action of verbascoside obtained from Buddleja cordata against Staphylococcus aureus by killing kinetics and incorporation of precursors methods. Verbascoside induced lethal effect on S. aureus, by affecting protein synthesis and inhibiting leucine incorporation.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0378-8741
1872-7573
DOI:10.1016/S0378-8741(98)00203-7