The effective connectivity of the default mode network following moderate traumatic brain injury

The effective connectivity can reveal the causal relationships between nodes of the Default Mode Network (DMN), which may reveal any impairment to the network following moderate traumatic brain injury (MTBI). Eight sub-acute MTBI patients and eight controls were recruited for this study. The results...

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Bibliographic Details
Published inJournal of physics. Conference series Vol. 1497; no. 1; pp. 12008 - 12011
Main Authors Abdul Rahman, M R, Abd Hamid, A I, Noh, N A, Idris, Z, Abdullah, J M
Format Journal Article
LanguageEnglish
Published Bristol IOP Publishing 01.03.2020
Subjects
Brain
Connectivity
Head injuries
Network hubs
Physics
Traumatic brain injury
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Summary:The effective connectivity can reveal the causal relationships between nodes of the Default Mode Network (DMN), which may reveal any impairment to the network following moderate traumatic brain injury (MTBI). Eight sub-acute MTBI patients and eight controls were recruited for this study. The results indicated that effective connectivity (EC) within MTBI group was higher in number and strength compared to the controls. Moreover, the network hubs within DMN are associated with increased connection strength in MTBI group. The ECs in MTBI are also largely influenced by top-down backward connections. In conclusion, the network reorganization within the DMN reflects the effect of MTBI and may subsequently impair other brain functions. This knowledge can be used to correctly identify the patient for appropriate trauma management.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/1497/1/012008