The Effects of High Hydrostatic Pressure on the Microtubules of Tetrahymena pyriformis

Exposure of Tetrahymena pyriformis to 7,500 or 10,000 psi of hydrostatic pressure for 2, 5, or 10 min intervals results in a change in cell shape and ciliary activity. Shape changes occur concurrently with a degradation of longitudinal microtubules in a posterior to anterior direction. High pressure...

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Bibliographic Details
Published inThe Journal of cell biology Vol. 47; no. 3; pp. 568 - 576
Main Authors Kennedy, John R., Zimmerman, Arthur M.
Format Journal Article
LanguageEnglish
Published United States Rockefeller University Press 01.12.1970
The Rockefeller University Press
Subjects
Animals
Cells
Cilia
Cilia - cytology
Fine structure
Granular materials
High pressure
Hydrostatic pressure
Microtubules
Pressure effects
Pseudopodia
Water pressure
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Summary:Exposure of Tetrahymena pyriformis to 7,500 or 10,000 psi of hydrostatic pressure for 2, 5, or 10 min intervals results in a change in cell shape and ciliary activity. Shape changes occur concurrently with a degradation of longitudinal microtubules in a posterior to anterior direction. High pressure also causes a disruption of ciliary activity. Fine structural analysis reveals a breakdown (presumably microtubule depolymerization) of the central ciliary microtubules. The depolymerization begins at the junction of the central ciliary microtubules with the axosome and progresses distally along the ciliary shaft for a distance of about 0.5 μ.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0021-9525
1540-8140
DOI:10.1083/jcb.47.3.568