Diagnosis and treatment of vascular graft and endograft infections: a structured clinical approach

• Published in: International journal of infectious diseases Vol. 126; pp. 22 - 27
• Main Authors: Wouthuyzen-Bakker, Marjan, van Oosten, Marleen, Bierman, Wouter, Winter, Rik, Glaudemans, Andor, Slart, Riemer, Toren-Wielema, Marlous, Tielliu, Ignace, Zeebregts, Clark J., Prakken, Niek H.J., de Vries, Jean Paul, Saleem, Ben R.
• Format: Journal Article
• Language: English
• Published: Canada Elsevier Ltd 01.01.2023; Elsevier
• Subjects: Antibiotic treatment; Blood Vessel Prosthesis - adverse effects; Blood Vessel Prosthesis Implantation - adverse effects; Diagnosis; Endograft infection; Endovascular Procedures - adverse effects; Humans; Prosthesis-Related Infections - diagnosis; Prosthesis-Related Infections - drug therapy; Prosthesis-Related Infections - surgery; Surgical treatment; Treatment Outcome; Vascular Diseases - etiology; Vascular graft infection; Vascular Grafting; Antibiotic treatment; Vascular graft infection; Diagnosis; Surgical treatment; Endograft infection
• ISSN: 1201-9712; 1878-3511
• DOI: 10.1016/j.ijid.2022.11.011

•Vascular graft or endograft infection (VGEI) is associated with high morbidity and mortality rates.•VGEI patients should be managed within a multidisciplinary team.•A structural diagnostic and treatment algorithm for VGEI is mandatory. A vascular graft or endograft infection (VGEI) is a severe complication that can occur after vascular graft or endograft surgery and is associated with high morbidity and mortality rates. A multidisciplinary approach, consisting of a team of vascular surgeons, infectious diseases specialists, medical microbiologists, radiologists, nuclear medicine specialists, and hospital pharmacists, is needed to adequately diagnose and treat VGEI. A structured diagnostic, antibiotic, and surgical treatment algorithm helps clinical decision making and ultimately aims to improve the clinical outcome of patients with a VGEI.