Total severity score and age predict long-term hospitalization in COVID-19 pneumonia
Severe COVID-19 pneumonia implies increased oxygen demands and length of hospitalization (LOS). We aimed to assess a possible correlation between LOS and COVID-19 patients' clinical laboratory data of admission, including the total severity score (TSS) from chest computed tomography (CT). Data...
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Published in | Frontiers in medicine Vol. 10; p. 1103701 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Switzerland
Frontiers Media S.A
12.04.2023
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Subjects | |
Online Access | Get full text |
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Summary: | Severe COVID-19 pneumonia implies increased oxygen demands and length of hospitalization (LOS). We aimed to assess a possible correlation between LOS and COVID-19 patients' clinical laboratory data of admission, including the total severity score (TSS) from chest computed tomography (CT).
Data were assessed retrospectively at the General Hospital "Agios Pavlos" in Greece. Clinical laboratory data, TSS, and LOS were recorded.
A total of 317 patients, 136 women and 181 men, with a mean age of 66.58 ± 16.02 years were studied. Significant comorbidities were hypertension (56.5%), dyslipidemia (33.8%), type 2 diabetes mellitus (22.7%), coronary heart disease (12.9%), underlying pulmonary disease (10.1%), and malignancy (4.4%). Inpatient time was related to age (
< 0.001), TSS (
< 0.001), time from symptom onset to hospitalization (
= 0.006), inhaled oxygen fraction (
< 0.001), fibrinogen (
= 0.024), d-dimers (
< 0.001), and C-reactive protein (
= 0.025), as well as a history of hypertension (
< 0.001) and type 2 diabetes mellitus (
< 0.008). The multivariate analysis showed a significant association of the LOS with age (
< 0.001) and TSS (
< 0.001) independent of the above-mentioned factors.
Early identification of disease severity using the TSS and patients' age could be useful for inpatient resource allocation and for maintaining vigilance for those requiring long-term hospitalizations. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 These authors have contributed equally to this work and share first authorship This article was submitted to Intensive Care Medicine and Anesthesiology, a section of the journal Frontiers in Medicine Edited by: Alfonso J. Rodriguez-Morales, Fundacion Universitaria Autónoma de las Américas, Colombia Reviewed by: Amir Afsahi, University of California, San Diego, United States; Anastasios Doulamis, National Technical University of Athens, Greece |
ISSN: | 2296-858X 2296-858X |
DOI: | 10.3389/fmed.2023.1103701 |