Implications of the long interdialytic gap: a problem of excess accumulation vs. excess removal?

Evidence suggests that patients receiving intermittent maintenance hemodialysis treatments experience higher mortality the day after the long 2-day interdialytic gap. A new study confirms higher mortality and reports increased hospitalization immediately after the long interdialytic interval among i...

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Bibliographic Details
Published inKidney international Vol. 88; no. 3; pp. 442 - 444
Main Authors Rhee, Connie M., Kalantar-Zadeh, Kamyar
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.09.2015
Elsevier Limited
Subjects
Female
Hospitalization
Humans
Male
Renal Dialysis
Water-Electrolyte Imbalance - therapy
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Summary:Evidence suggests that patients receiving intermittent maintenance hemodialysis treatments experience higher mortality the day after the long 2-day interdialytic gap. A new study confirms higher mortality and reports increased hospitalization immediately after the long interdialytic interval among incident hemodialysis patients in the United Kingdom. Larger fluid accumulation followed by excessive ultrafiltration and abrupt fluctuations in serum potassium concentrations may be among potential factors contributing to the morbidity and mortality of this precarious period.
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ISSN:0085-2538
1523-1755
1523-1755
DOI:10.1038/ki.2015.193