Pathophysiological role of osteopontin and angiotensin II in atherosclerosis

•This review includes some new mechanisms of Atherosclerosis.•In the context of atherosclerosis, OPN and Ang II is generally regarded as a proinflammatory and proatherogenic molecule.•The most highlight is we reviewed the mechanism that OPN modulates Ang II-induced inflammation in Atherosclerosis....

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Published inBiochemical and biophysical research communications Vol. 471; no. 1; pp. 5 - 9
Main Authors Ding, Yulong, Chen, Jianing, Cui, Guangying, Wei, Yingfeng, Lu, Chong, Wang, Lin, Diao, Hongyan
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 26.02.2016
Subjects
Angiotensin II
Angiotensin II - immunology
Animals
Atherosclerosis
Atherosclerosis - immunology
Humans
Immunologic Factors - immunology
Models, Cardiovascular
Models, Immunological
Osteopontin
Osteopontin - immunology
Vasculitis - immunology
Osteopontin
Angiotensin II
Atherosclerosis
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Summary:•This review includes some new mechanisms of Atherosclerosis.•In the context of atherosclerosis, OPN and Ang II is generally regarded as a proinflammatory and proatherogenic molecule.•The most highlight is we reviewed the mechanism that OPN modulates Ang II-induced inflammation in Atherosclerosis.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0006-291X
1090-2104
DOI:10.1016/j.bbrc.2016.01.142