Role of gold nanoparticles in advanced biomedical applications
Gold nanoparticles (GNPs) have generated keen interest among researchers in recent years due to their excellent physicochemical properties. In general, GNPs are biocompatible, amenable to desired functionalization, non-corroding, and exhibit size and shape dependent optical and electronic properties...
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| Published in | Nanoscale advances Vol. 2; no. 9; pp. 3764 - 3787 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
RSC
16.09.2020
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| Subjects | |
| Online Access | Get full text |
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| Summary: | Gold nanoparticles (GNPs) have generated keen interest among researchers in recent years due to their excellent physicochemical properties. In general, GNPs are biocompatible, amenable to desired functionalization, non-corroding, and exhibit size and shape dependent optical and electronic properties. These excellent properties of GNPs exhibit their tremendous potential for use in diverse biomedical applications. Herein, we have evaluated the recent advancements of GNPs to highlight their exceptional potential in the biomedical field. Special focus has been given to emerging biomedical applications including bio-imaging, site specific drug/gene delivery, nano-sensing, diagnostics, photon induced therapeutics, and theranostics. We have also elaborated on the basics, presented a historical preview, and discussed the synthesis strategies, functionalization methods, stabilization techniques, and key properties of GNPs. Lastly, we have concluded this article with key findings and unaddressed challenges. Overall, this review is a complete package to understand the importance and achievements of GNPs in the biomedical field.
Gold nanoparticles (GNPs) have generated keen interest among researchers in recent years due to their excellent physicochemical properties. |
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| Bibliography: | Presently, he is an assistant professor (& head of the nano/micro-manufacturing and materials research group) at Maharaja Agrasen University. He has published more than 20 research papers, holds 1 patent and has served as a subject expert for a number of journals. Dr Suneev Anil Bansal has more than 15 years of diverse experience in industry, research laboratories and academia. He has served in key positions in key projects like automobile development at Hero Motor Corp., fighter aircraft development at DRDO, and nanomaterials & manufacturing development at various universities. His research interest is in the fields of micro/nano-manufacturing, materials, 2D materials, graphene, polymer/metal composite materials, sensing etc. Dr Vanish Kumar is presently working as an INSPIRE faculty member at the National Agri-Food Biotechnology Institute (NABI), Mohali, India. He has an M. Tech degree in nanoscience and nanotechnology. He completed his PhD (Engineering) from CSIR-CSIO, Chandigarh, India. His current areas of research include development of nanosensing platforms, synthesis of advanced nanostructures, and analytical applications of nanomaterials. He has published more than 50 research papers in reputed international journals. mechanics of composites, fracture mechanics, system modeling, automation, and controlled machining for delamination-free drilling of polymer composites. Dr Javad Karimi is currently an Assistant Professor at Shiraz University, Iran. He received his Bachelor's degree in biology from Isfahan University, Iran. He received his Master's and PhD degrees in plant physiology from Shiraz University, Iran. His current research interests focus on the areas of plant physiology, biotechnology and nano-biotechnology. He has published more than 20 research papers in reputed international journals. Prof. Amrinder Pal Singh is a professor of mechanical engineering at UIET, Panjab University, Chandigarh. He has more than 21 years of teaching experience with 8 years of research experience. His research interests include polymer composites including nanocomposites for engineering applications under dynamic loading and impact loading conditions, strain sensing, wearable sensors Dr Suresh Kumar is an assistant professor at the University Institute of Engineering and Technology (UIET), Panjab University, Chandigarh. He did his PhD at Panjab University, Chandigarh/Central Scientific Instruments Organisation, Chandigarh, India and postdoctoral training at the Indian Institute of Science, Bangalore, India. His research interests include application of nanotechnology with special emphasis on development of biosensors, gas sensors, wearable electronics and energy storage/harvesting devices. He has several publications to his credit. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 |
| ISSN: | 2516-0230 2516-0230 |
| DOI: | 10.1039/d0na00472c |