First use of a drug-eluting balloon in the treatment of acute renal artery occlusion and in-stent restenosis

In-stent restenosis in a renal artery (RA) of a solitary functioning kidney is a serious complication of RA stenting. Drug-eluting balloons (DEB) have emerged as a novel way to manage restenosis. In this paper, the authors reported the first use of a DEB in the treatment of severe in-stent restenosi...

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Published inThe American journal of the medical sciences Vol. 346; no. 3; p. 244
Main Authors Itani, Houssam S, Mudawwar, Walid A, Tanios, Bassem Y, Alam, Samir E, Haddad, Fady F
Format Journal Article
LanguageEnglish
Published United States 01.09.2013
Subjects
Angioplasty, Balloon
Drug Delivery Systems
Female
Fibrinolytic Agents - administration & dosage
Humans
Middle Aged
Renal Artery
Renal Artery Obstruction - diagnosis
Renal Artery Obstruction - etiology
Renal Artery Obstruction - therapy
Stents - adverse effects
Thrombosis - diagnosis
Thrombosis - etiology
Thrombosis - therapy
Tissue Plasminogen Activator - administration & dosage
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Summary:In-stent restenosis in a renal artery (RA) of a solitary functioning kidney is a serious complication of RA stenting. Drug-eluting balloons (DEB) have emerged as a novel way to manage restenosis. In this paper, the authors reported the first use of a DEB in the treatment of severe in-stent restenosis and thrombosis of a drug-eluting stent deployed in a RA. The patient presented with oligo-anuria and a serum creatinine (Scr) of 9 mg/dL that improved back to baseline of 2 mg/dL after the successful procedure. The optimal use of DEB in similar cases will have to be determined by larger clinical trials.
ISSN:1538-2990
DOI:10.1097/MAJ.0b013e31828b2b7f