Long Slender Cytoplasmic Extensions: A Common Feature of Neuroendocrine Cells?
We have recently developed a new method for visualisation of gut mucosal cells and demonstrated that enterochromaffin (EC) and enterochromaffin‐like (ECL) cells possess cytoplasmic extensions. The aim of the present study was to characterise the morphology of D‐ and G‐cells. The D‐cells in the stoma...
Saved in:
Published in | Journal of neuroendocrinology Vol. 19; no. 9; pp. 739 - 742 |
---|---|
Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Oxford, UK
Blackwell Publishing Ltd
01.09.2007
Blackwell Science |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | We have recently developed a new method for visualisation of gut mucosal cells and demonstrated that enterochromaffin (EC) and enterochromaffin‐like (ECL) cells possess cytoplasmic extensions. The aim of the present study was to characterise the morphology of D‐ and G‐cells. The D‐cells in the stomach differed morphologically from intestinal D‐cells, suggesting two distinct subpopulations of D‐cells. Some D‐cells appeared to be interconnected. No cell‐to‐cell contact between parietal and D‐cells was found. Both D‐ and G‐cells possessed long cytoplasmic extensions corresponding with our previous descriptions of EC and ECL cells. We propose that all neuroendocrine cells have the ability to develop cytoplasmic extensions, enabling them to signal to their target cells in a neurocrine manner. |
---|---|
Bibliography: | ark:/67375/WNG-784SKQLJ-J istex:01B193BD107F5F89BFEBB0111C608210AFDEDC21 ArticleID:JNE1578 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0953-8194 1365-2826 |
DOI: | 10.1111/j.1365-2826.2007.01578.x |