Extraskeletal Osteosarcoma of the Hand: The Role of Marginal Excision and Adjuvant Radiation Therapy

• Published in: HAND Vol. 10; no. 4; pp. 602 - 606
• Main Authors: Casey, Dana L., van de Rijn, Matt, Riley, Geoffrey, Tung, Ka-Wah, Mohler, David G., Donaldson, Sarah S.
• Format: Book Review Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.12.2015; Springer US
• Subjects: Medicine; Medicine & Public Health; Orthopedics; Plastic Surgery; Review; Surgery; Surgical Orthopedics; Soft tissue sarcoma; Limb salvage; Radiation therapy; Osteosarcoma; Hand
• ISSN: 1558-9447; 1558-9455
• DOI: 10.1007/s11552-015-9760-0

Background Extraskeletal osteosarcoma of the hand is rare, and its optimal modality of local control is not currently known. Methods A literature search was performed to identify studies that describe the treatment and outcomes of extraskeletal osteosarcoma. A second literature search was performed to identify studies that describe the treatment and outcomes of extraskeletal osteosarcoma of the hand specifically. Results The role of adjuvant radiation for extraskeletal osteosarcoma is not well defined. All cases in the literature describing treatment of extraskeletal osteosarcoma of the hand utilized amputation, and none of the patients described received radiation therapy. However, there are multiple reports showing excellent local control, minimal toxicity, and superior functional outcome with limb conservation and radiation rather than amputation of the hand in pediatric and adult soft tissue sarcoma. Conclusion For extraskeletal osteosarcoma of the hand, we recommend a treatment approach with the goal of preservation of form and function using limb-sparing surgery and planned postoperative radiation.