Binding studies of an arabinogalactan-protein from Echinacea purpurea to leucocytes
Flow cytometric investigations show binding of an isolated arabinogalactan-protein (AGP) from pressed juice of the aerial parts of Echinacea purpurea to the cell surface of human leucocytes. AGP demonstrates binding to lymphocytes, monocytes and granulocytes of different donors ( n=8). Competition a...
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Published in | Phytomedicine (Stuttgart) Vol. 13; no. 6; pp. 425 - 427 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Germany
Elsevier GmbH
01.06.2006
Urban & Fischer Verlag |
Subjects | |
Online Access | Get full text |
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Summary: | Flow cytometric investigations show binding of an isolated arabinogalactan-protein (AGP) from pressed juice of the aerial parts of
Echinacea purpurea to the cell surface of human leucocytes. AGP demonstrates binding to lymphocytes, monocytes and granulocytes of different donors (
n=8). Competition assays with two antibodies, directed against CD4 and CD8, revealed no interaction of AGP with these receptors, leading to the conclusion that binding of AGP to leucocytes is mediated via other structures. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0944-7113 1618-095X |
DOI: | 10.1016/j.phymed.2005.01.017 |