Area postrema syndrome: Another feature of anti-GFAP encephalomyelitis

Anti-Glial fibrillary acidic protein (GFAP) encephalomyelitis is a recently described entity and while the spectrum of this disease has been explored, further research is needed to fully describe its phenotype. Area postrema syndrome (APS) is usually associated with neuromyelitis optica spectrum dis...

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Published inMultiple sclerosis Vol. 26; no. 2; p. 253
Main Authors Ciron, Jonathan, Sourdrille, Fanny, Biotti, Damien, Tchoumi, Thierry, Ruiz, Anne, Bernard-Valnet, Raphaël, Maubeuge, Nicolas, Marignier, Romain
Format Journal Article
LanguageEnglish
Published England 01.02.2020
Subjects
Adult
Area Postrema
Autoantibodies - immunology
Autoantigens - immunology
Encephalomyelitis - complications
Encephalomyelitis - immunology
Encephalomyelitis - pathology
Female
Glial Fibrillary Acidic Protein - immunology
Humans
Nausea - immunology
Syndrome
Vomiting - immunology
anti-GFAP encephalomyelitis
Area postrema syndrome
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Summary:Anti-Glial fibrillary acidic protein (GFAP) encephalomyelitis is a recently described entity and while the spectrum of this disease has been explored, further research is needed to fully describe its phenotype. Area postrema syndrome (APS) is usually associated with neuromyelitis optica spectrum disorders (NMOSDs), whereas no case of APS has been previously reported with anti-GFAP encephalomyelitis. In this article, we report a case of APS in a 41-year-old woman in the context of anti-GFAP encephalomyelitis. This case was not associated with additional anti-AQP4 IgG and therefore extends the clinico-radiological spectrum of anti-GFAP encephalomyelitis.
ISSN:1477-0970
DOI:10.1177/1352458518817992