Felt Stigma and Its Underlying Contributors in Epilepsy Patients
To explore the correlated clinical and psychological factors of stigmatization and investigate the relationship between stigma and white matter abnormalities in epilepsy patients. Stigmatization was obtained by a three-item stigma scale in 256 epilepsy patients with genetic or unknown etiology. Pers...
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Published in | Frontiers in public health Vol. 10; p. 879895 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Switzerland
Frontiers Media S.A
26.04.2022
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Subjects | |
Online Access | Get full text |
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Summary: | To explore the correlated clinical and psychological factors of stigmatization and investigate the relationship between stigma and white matter abnormalities in epilepsy patients.
Stigmatization was obtained by a three-item stigma scale in 256 epilepsy patients with genetic or unknown etiology. Personality and quality of life (QOL) were assessed by Eysenck Personality Questionnaire (EPQ) and QOL-31 questionnaire respectively. One hundred and fourteen of them were performed Hamilton Depression Scale-17 (HAMD) and scanned with diffusion tensor imaging in 3T MRI. Fractional anisotropy (FA) values of frontotemporal contact fibers were calculated.
There were about 39.8% patients felt stigma, with the highest score (Score 3) in 8.2% (21/256). Stigma scores were significantly negatively correlated with education (
< 0.01), age of onset (
< 0.05), extraversion score of EPQ (
< 0.01), total and all the subscale QOL scores (
< 0.001), and positively correlated with duration (
< 0.01), HAMD score (
< 0.001), neuroticism score of EPQ (
< 0.001). We found negative correlation between stigma scores and FA values of right superior longitudinal fasciculus and left cingulum (
< 0.05). Logistic regression results showed that FA value of left cingulum (
= 0.011; OR = 0.000), social function (
= 0.000; OR = 0.935) of QOL, and neuroticism score of EPQ (
= 0.033; OR = 1.123) independently correlated to felt stigma.
Felt stigma in epilepsy patients was found to be correlated with neuroticism, depression, and deficient social function of QOL, which might be predisposed by the impairment of the left cingulum. Our results provide preliminary evidence for the underlying neural circuits in stigmatization. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 This article was submitted to Public Mental Health, a section of the journal Frontiers in Public Health These authors have contributed equally to this work Edited by: Wulf Rössler, Charité Universitätsmedizin Berlin, Germany Reviewed by: Jacopo Lanzone, Sant'Isidoro Hospital Ferb Onlus Trescore Balneario, Italy; Ekaterina Viteva, Plovdiv Medical University, Bulgaria; Gloria Tedrus, Pontifical Catholic University of Campinas, Brazil |
ISSN: | 2296-2565 2296-2565 |
DOI: | 10.3389/fpubh.2022.879895 |