Derivatives of Plastics as Potential Carcinogenic Factors: The Current State of Knowledge

Micro- and nanoplatics have been already reported to be potential carcinogenic/mutagenic substances that might cause DNA damage, leading to carcinogenesis. Thus, the effects of micro- and nanoplastics exposure on human health are currently being investigated extensively to establish clear relationsh...

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Published inCancers Vol. 14; no. 19; p. 4637
Main Authors Baj, Jacek, Dring, James Curtis, Czeczelewski, Marcin, Kozyra, Paweł, Forma, Alicja, Flieger, Jolanta, Kowalska, Beata, Buszewicz, Grzegorz, Teresiński, Grzegorz
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 24.09.2022
MDPI
Subjects
Adenocarcinoma
Aluminum
Biliary tract
Carcinogenesis
Causes of
Chemical contaminants
Contamination
DNA damage
Flame retardants
Food contamination & poisoning
Heavy metals
Hepatocellular carcinoma
High density polyethylenes
Inhalation
Liver cancer
Pancreatic cancer
Pancreatic carcinoma
Plastic pollution
Pollutants
Polyethylene
Polymers
Review
Poland
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ISSN2072-6694
2072-6694
DOI10.3390/cancers14194637

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Summary:Micro- and nanoplatics have been already reported to be potential carcinogenic/mutagenic substances that might cause DNA damage, leading to carcinogenesis. Thus, the effects of micro- and nanoplastics exposure on human health are currently being investigated extensively to establish clear relationships between those substances and health consequences. So far, it has been observed that there exists a definite correlation between exposure to micro- and nanoplastic particles and the onset of several cancers. Therefore, we have conducted research using PubMed, Web of Science, and Scopus databases, searching for all the research papers devoted to cancers that could be potentially related to the subject of exposure to nano- and microplastics. Ultimately, in this paper, we have discussed several cancers, including hepatocellular carcinoma, pancreatic cancer, pancreatic ductal adenocarcinoma, biliary tract cancer, and some endocrine-related cancers.
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ISSN:2072-6694
2072-6694
DOI:10.3390/cancers14194637